SCHEMBL4799535

SCHEMBL4799535

CC(C)OC(=O)C(C(=O)OC(C)C)=C1c2ccccc2-c2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 1/20 0.48
PDE4D Q08499 1/20 0.48
NPC1 O15118 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
GAA P10253 1/20 0.46
TSHR P16473 2/20 0.43
PDCD1 Q15116 1/20 0.42
CD274 Q9NZQ7 1/20 0.42
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
CA14 Q9ULX7 2/20 0.41
ALDH1A1 P00352 2/20 0.40
AGTR1 P30556 1/20 0.40
S100A4 P26447 1/20 0.39
TDP2 O95551 1/20 0.39
NSD2 O96028 1/20 0.39
PLA2G1B P04054 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21908162 0.85 NPC1 (0.45) ADRA1APDE4DNPC1SMN1; SMN2GAA
SCHEMBL15470962 0.84 BCHE (0.50) ADRA1APDE4DNPC1SMN1; SMN2GAA
SCHEMBL15473384 0.79 IDO1 (0.46) NPC1SMN1; SMN2GAATSHRPDCD1
SCHEMBL15470937 0.77 IDO1 (0.41) SMN1; SMN2GAATSHRALDH1A1S100A4
SCHEMBL20262514 0.76 ALDH1A1 (0.53) NPC1SMN1; SMN2TSHRALDH1A1TDP2
SCHEMBL7637265 0.73 CES2 (0.52) NPC1SMN1; SMN2GAATSHRPDCD1
SCHEMBL16804198 0.72 MAPT (0.48) NPC1SMN1; SMN2ALDH1A1S100A4TDP2
SCHEMBL20262437 0.72 IDO1 (0.61) SMN1; SMN2GAATSHRALDH1A1HSP90AA1
SCHEMBL20262489 0.72 ADRA1A (0.44) ADRA1APDE4DNPC1SMN1; SMN2GAA
SCHEMBL20262451 0.69 ALDH1A1 (0.52) SMN1; SMN2GAATSHRALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10308563-B2 Process for producing ethylene oligomers HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2019-06-04 US disclosed
US-20180170827-A1 PROCESS FOR PRODUCING ETHYLENE OLIGOMERS HANWHA TOTALENERGIES PETROCHEMICAL CO., LTD. (KR) 2018-06-21 US disclosed
US-20180169642-A1 CATALYST SYSTEM FOR ETHYLENE OLIGOMERIZATION AND METHOD FOR PRODUCING ETHYLENE OLIGOMERIZATION USING THE SAME HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2018-06-21 US disclosed
US-7431917-B2 Photostable photoprotective compositions comprising dibenzoylmethane and bis-resorcinyl triazine compounds and a compound that accepts the excited triplet level energy of said dibenzoylmethane(s) L'OREAL (FR) 2008-10-07 US disclosed
US-7357920-B2 Photostable photoprotective compositions comprising dibenzoylmethane and amide oil compounds and a compound that accepts the excited triplet level energy of said dibenzoylmethane(s) L'OREAL (FR) 2008-04-15 US disclosed
US-7357919-B2 Photostable photoprotective compositions comprising dibenzoylmethane and arylalkyl benzoate compounds and a compound that accepts the excited triplet level energy of said dibenzoylmethane(s) L'OREAL (FR) 2008-04-15 US disclosed
EP-1539064-B1 NOVEL PHOTOSTABILIZERS, UV ABSORBERS, AND METHODS OF PHOTOSTABILIZING A SUNSCREEN COMPOSITION CPH INNOVATIONS CORP (US) 2007-02-21 EP disclosed
US-20060104924-A1 Photostable photoprotective compositions comprising dibenzoylmethane and arylalkyl benzoate compounds and a compound that accepts the excited triplet level energy of said dibenzoylmethane(s) L'OREAL (FR) 2006-05-18 US disclosed
EP-1649902-A2 Light screening composition comprising a dibenzoylmethane derivative, an arylalkyl benzoat derivative and a compound capable of accepting energie from the excited triplet state of dibenzoylmethane; process of photostabilisation L'OREAL (FR) 2006-04-26 EP disclosed
EP-1649901-A2 Light screening composition comprising a dibenzoylmethane derivative, a lipophilic amide and a compound capable of accepting energy from the excited triplet state of dibenzoylmethane; process for photostabilsation L'OREAL (FR) 2006-04-26 EP disclosed
US-6926887-B2 Photostabilizers, UV absorbers, and methods of photostabilizing a sunscreen composition THE C.P. HALL COMPANY (US) 2005-08-09 US disclosed
US-6919473-B2 Photostabilizers, UV absorbers, and methods of photostabilizing a sunscreen composition CPH INNOVATIONS CORPORATION (US) 2005-07-19 US disclosed
EP-1539064-A2 NOVEL PHOTOSTABILIZERS, UV ABSORBERS, AND METHODS OF PHOTOSTABILIZING A SUNSCREEN COMPOSITION CPH Innovations Corp. (US) 2005-06-15 EP disclosed
WO-2004110394-A2 NOVELL PHOTOSTABILIZERS, UV ABSORBERS, AND METHODS OF PHOTOSTABILIZING A SUNSCREEN COMPOSITION CPH INNOVATIONS CORP. (US) 2004-12-23 WO disclosed
US-6800274-B2 UNSATURATED ESTERS INCLUDING DIPHENYLMETHYLENE AND/OR 9H-FLUORENE MOIETIES THE C.P. HALL COMPANY 2004-10-05 US disclosed
WO-2004026197-A2 NOVEL PHOTOSTABILIZERS, UV ABSORBERS, AND METHODS OF PHOTOSTABILIZING A SUNSCREEN COMPOSITION CPH INNOVATIONS CORPORATION (US) 2004-04-01 WO disclosed
US-20040062726-A1 Novel photostabilizers, UV absorbers, and methods of photostabilizing a sunscreen composition BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2004-04-01 US disclosed
US-20040057916-A1 Novel photostabilizers, UV absorbers, and methods of photostablizing a sunscreen composition THE C.P. HALL COMPANY 2004-03-25 US disclosed
US-20040057912-A1 Novel photostabilizers, UV absorbers, and methods of photostabilizing a sunscreen composition BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2004-03-25 US disclosed
US-20040057914-A1 Novel photostabilizers, UV absorbers, and methods of photostabilizing a sunscreen composition BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2004-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040057912-A1 Novel photostabilizers, UV absorbers, and methods of photostabilizing a sunscreen composition UROD, ALAD, HMBS ADRA1A 3785/4885PDE4D 3199/4885NPC1 1618/4885
US-20040057916-A1 Novel photostabilizers, UV absorbers, and methods of photostablizing a sunscreen composition UROD, UNG, ALAD ADRA1A 4198/4885PDE4D 4226/4885NPC1 2489/4885
US-10308563-B2 Process for producing ethylene oligomers OXER1, HAO2, ORC3 ADRA1A 1544/4885PDE4D 4885/4885NPC1 1536/4885
US-20040057914-A1 Novel photostabilizers, UV absorbers, and methods of photostabilizing a sunscreen composition UROD, UNG, HMBS ADRA1A 4407/4885PDE4D 3097/4885NPC1 2415/4885
US-20060104924-A1 Photostable photoprotective compositions comprising dibenzoylmethane and arylalkyl benzoate compounds and a compound that accepts the excited triplet level energy of said dibenzoylmethane(s) DDT, TYR, CUTA ADRA1A 4069/4885PDE4D 3946/4885NPC1 2048/4885
US-20180169642-A1 CATALYST SYSTEM FOR ETHYLENE OLIGOMERIZATION AND METHOD FOR PRODUCING ETHYLENE OLIGOMERIZATION USING THE SAME HACL2, HAO2, MSMO1 ADRA1A 2532/4885PDE4D 4885/4885NPC1 1894/4885
US-20180170827-A1 PROCESS FOR PRODUCING ETHYLENE OLIGOMERS OXER1, HAO2, ORC3 ADRA1A 1544/4885PDE4D 4885/4885NPC1 1536/4885
US-20040062726-A1 Novel photostabilizers, UV absorbers, and methods of photostabilizing a sunscreen composition UROD, ALAD, UNG ADRA1A 3497/4885PDE4D 2476/4885NPC1 1391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.