Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | RXRG | P48443 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2254157 | 0.89 | KDM4E (0.42) | VCAM1RXRARXRBRXRGNPSR1 | |
| Adipic Acid SCHEMBL7993766 | 0.82 | VCAM1 (0.55) | VCAM1MAPK1SMN1; SMN2NPSR1GLRA3 | |
| Adipic Acid SCHEMBL28216161 | 0.82 | VCAM1 (0.55) | VCAM1MAPK1SMN1; SMN2NPSR1GLRA3 | |
| SCHEMBL28353915 | 0.79 | GAA (0.41) | SMN1; SMN2GLRA3GLRBKDM4EALDH1A1 | |
| SCHEMBL28654562 | 0.79 | ALDH1A1 (0.38) | SLC6A3SMN1; SMN2GLRA3GLRBKDM4E | |
| SCHEMBL1815047 | 0.78 | GLRA3 (0.42) | RXRARXRBRXRGSMN1; SMN2GLRA3 | |
| SCHEMBL30640814 | 0.78 | HTT (0.47) | MAPK1SMN1; SMN2NPSR1KDM4EALDH1A1 | |
| SCHEMBL1278250 | 0.76 | GAA (0.58) | VCAM1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL5038246 | 0.76 | KDM4E (0.46) | SMN1; SMN2KDM4EALDH1A1CYP3A4HSD17B10 | |
| Stearic Acid SCHEMBL6938564 | 0.76 | GPR84 (0.53) | VCAM1HDAC11ALDH1A1ESR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7339003-B2 | Antioxidants and antioxidant boosters capable of producing hydroperoxyl radicals | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2008-03-04 | — | — | US | disclosed |
| US-20050145831-A1 | Antioxidants and antioxidant boosters capable of producing hydroperoxyl radicals | ALDRICH HAVEN S (US) | 2005-07-07 | — | — | US | disclosed |
| US-6689724-B2 | HIGH NUMBER OF HYDROXYL POLYOL ESTERS ANTIOXIDANTS WHEN GRAFTED ONTO MINERAL OILS, POLYOL ESTERS, POLYALPHA OLEFIN BASE STOCKS, FUELS, OLIGOMERS AND POLYMERS CAN INCREASE THE OXIDATION STABILITY; LUBRICANTS; OIL ADDITIVES | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2004-02-10 | — | — | US | disclosed |
| WO-2002092734-A1 | ANTIOXIDANTS AND ANTIOXIDANT BOOSTERS CAPABLE OF PRODUCING HYDROPEROXYL RADICALS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2002-11-21 | — | — | WO | disclosed |
| US-20020082174-A1 | Antioxidants and antioxidant boosters capable of producing hydroperoxyl radicals | EXXONMOBIL RESEARCH & ENGINEERING CO. | 2002-06-27 | — | — | US | disclosed |
| EP-0946689-A4 | ANTIOXIDANTS AND ANTIOXIDANT BOOSTERS CAPABLE OF PRODUCING HYDROPEROXYL RADICALS | EXXON RESEARCH ENGINEERING CO (US) | 2000-11-22 | — | — | EP | disclosed |
| EP-0946689-A1 | ANTIOXIDANTS AND ANTIOXIDANT BOOSTERS CAPABLE OF PRODUCING HYDROPEROXYL RADICALS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998011181-A1 | ANTIOXIDANTS AND ANTIOXIDANT BOOSTERS CAPABLE OF PRODUCING HYDROPEROXYL RADICALS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1998-03-19 | — | — | WO | disclosed |
| EP-0393239-A2 | Polysiloxanes with pendant sterically hindered phenol moiety connected to the silicon atom via a carbonyloxy-containing link | UNION CARBIDE CORPORATION (US) | 1990-10-24 | — | — | EP | disclosed |
| EP-0390153-A2 | Polymer compositions stabilized with polydialkylsiloxanes containing siloxy units having certain defined pendant sterically hindered phenol moieties | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) | 1990-10-03 | — | — | EP | disclosed |
| US-4960810-A | Polymer compositions stabilized with polydialkylsiloxanes containing siloxy units having certain defined pendant sterically hindered phenol moieties | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) | 1990-10-02 | — | — | US | disclosed |
| US-4879378-A | STABILIZERS | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) | 1989-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020082174-A1 | Antioxidants and antioxidant boosters capable of producing hydroperoxyl radicals | GPX4, LPO, CAT | VCAM1 4006/4885RXRA 1908/4885RXRB 2131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.