Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11409716 | 0.90 | NLRP3 (0.45) | TSHRSMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL11281869 | 0.90 | LMNA (0.40) | TSHRLMNASMN1; SMN2PIN1KMT2A | |
| SCHEMBL11416335 | 0.83 | SMN1; SMN2 (0.39) | TSHRSMN1; SMN2KMT2AALDH1A1GAA | |
| SCHEMBL998674 | 0.83 | KMT2A (0.43) | TSHRKMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL11286164 | 0.83 | ALDH1A1 (0.49) | LMNAKMT2AALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11285004 | 0.79 | L3MBTL1 (0.44) | LMNASMN1; SMN2KMT2AALDH1A1GAA | |
| SCHEMBL4016238 | 0.77 | PTGS2 (0.46) | TSHRLMNASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL11043246 | 0.75 | EPHX1 (0.37) | TSHRKMT2ATDP1L3MBTL1POLB | |
| SCHEMBL11276127 | 0.75 | GAA (0.41) | SMN1; SMN2ALDH1A1GAAHPGDNPC1 | |
| SCHEMBL3539652 | 0.75 | SLC6A2 (0.44) | TSHRLMNAKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323563-B2 | Hydroxamic acid derivatives as antibacterials | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2008-01-29 | — | — | US | disclosed |
| EP-1754477-A2 | Hydroxamic acid derivatives as antibacterials | Vernalis (Oxford) Limited (GB) | 2007-02-21 | — | — | EP | disclosed |
| EP-1079819-B1 | HYDROXAMIC ACID DERIVATIVES AS ANTIBACTERIALS | VERNALIS OXFORD LTD (GB) | 2006-12-06 | — | — | EP | disclosed |
| US-20060211732-A1 | Hydroxamic acid derivatives as antibacterials | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2006-09-21 | — | — | US | disclosed |
| US-6992190-B2 | Hydroxamic acid derivatives as antibacterials | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2006-01-31 | — | — | US | disclosed |
| US-20020198241-A1 | Hydroxamic acid derivatives as antibacterials | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2002-12-26 | — | — | US | disclosed |
| US-6441042-B1 | HYDROXYAMIDES | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2002-08-27 | — | — | US | disclosed |
| US-4348410-A | Cyclohexane carboxylic acid derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1982-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211732-A1 | Hydroxamic acid derivatives as antibacterials | SLC7A1, EGLN2, PIGS | TSHR 2357/4885LMNA 3846/4885SMN1; SMN2 1425/4885 |
| US-20020198241-A1 | Hydroxamic acid derivatives as antibacterials | SLC7A1, EGLN2, PIGS | TSHR 2326/4885LMNA 3748/4885SMN1; SMN2 1305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.