Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ESRRA | P11474 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417191 | 0.82 | THRA (0.46) | MAPTGAAL3MBTL1MEN1KMT2A | |
| SCHEMBL6330127 | 0.79 | TDP1 (0.45) | MRGPRX4MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9347220 | 0.76 | CA1 (0.40) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27738623 | 0.76 | MAPT (0.52) | ALDH1A1MAPTGAAL3MBTL1KMT2A | |
| SCHEMBL311716 | 0.75 | ADRB2 (0.60) | ADRB2ESRRAMRGPRX4ALDH1A1MAPK1 | |
| SCHEMBL18761557 | 0.74 | ESRRA (0.50) | ADRB2ESRRAMRGPRX4ALDH1A1MAPK1 | |
| SCHEMBL28694226 | 0.72 | SMN1; SMN2 (0.58) | ALDH1A1MAPK1GAAL3MBTL1MEN1 | |
| SCHEMBL8565904 | 0.72 | PDE7A (0.49) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL6314022 | 0.71 | ESRRA (0.48) | ADRB2ESRRAMRGPRX4ALDH1A1MAPK1 | |
| SCHEMBL3940201 | 0.71 | RORC (0.65) | ADRB2ESRRAMRGPRX4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363688-B1 | Novel phosphoric acid derivatives and a method for determination of acid phosphatase activity using the same | NITTO BOSEKI CO LTD (JP) | 1994-01-05 | — | — | EP | claimed |
| US-5081274-A | Tumor diagnosis | NITTO BOSEKI CO., LTD. (JP) | 1992-01-14 | — | — | US | claimed |
| US-7465556-B2 | Method of immunoassay tartrate resistant acid phosphatase 5b and kit to be used therein | NITTO BOSEKI CO., LTD. (JP) | 2008-12-16 | — | — | US | disclosed |
| EP-1598670-B1 | METHOD OF IMMUNOASSAYING TARTRATE RESISTANT ACID PHOSPHATASE 5b AND KIT TO BE USED THEREIN | NITTO BOSEKI CO LTD (JP) | 2007-06-20 | — | — | EP | disclosed |
| US-20060154317-A1 | Method of immunoassaying taritrate resistant acid phosphatase 5b and kit to be used therein | NITTO BOSEKI CO., LTD (JP) | 2006-07-13 | — | — | US | disclosed |
| EP-1598670-A1 | METHOD OF IMMUNOASSAYING TARTRATE RESISTANT ACID PHOSPHATASE 5b AND KIT TO BE USED THEREIN | NITTO BOSEKI CO., LTD. (JP) | 2005-11-23 | — | — | EP | disclosed |
| US-5719030-A | SUBTRACTING NON-PROSTATE DERIVED ACID PHOSPHATASE ACTIVITY MEASURED AFTER INHIBITION OF PROSTATE-DERIVED ACID PHOSPHATASE FROM MEASURED TOTAL ACID PHOSPHATASE ACTIVITY; SIMPLIFICATION | NITTO BOSEKI CO., LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0363688-B1 | Novel phosphoric acid derivatives and a method for determination of acid phosphatase activity using the same | NITTO BOSEKI CO LTD (JP) | 1994-01-05 | — | — | EP | disclosed |
| US-5227291-A | METHOD FOR DETERMINATION OF ACID PHOSPHATASE ACTIVITY USING 4-ACYL-2, 6-DIHALOPHENYL PHOSPHORIC ACID DERIVATIVES | NITTO BOSEKI CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| US-5151372-A | Measurement of UV absorbance in the presence of bilirubin or hemoglobin | NITTO BOSEKI CO., LTD. (JP) | 1992-09-29 | — | — | US | disclosed |
| US-5081274-A | Tumor diagnosis | NITTO BOSEKI CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0363688-A1 | Novel phosphoric acid derivatives and a method for determination of acid phosphatase activity using the same | NITTO BOSEKI CO., LTD. (JP) | 1990-04-18 | — | — | EP | disclosed |