SCHEMBL482796

SCHEMBL482796

Cc1cc(C)c(Br)cc1Br

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.42
CYP3A4 P08684 3/20 0.42
MAPK1 P28482 2/20 0.42
ALDH1A1 P00352 3/20 0.40
BCHE P06276 1/20 0.39
CES1 P23141 1/20 0.39
POLB P06746 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HTR2C P28335 2/20 0.33
CA2 P00918 2/20 0.33
CA4 P22748 2/20 0.33
NQO2 P16083 1/20 0.33
CA1 P00915 1/20 0.32
CA6 P23280 1/20 0.32
APEX1 P27695 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
HPGD P15428 1/20 0.31
TDP1 Q9NUW8 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL133345 0.89 TSHR (0.47) TSHRCYP3A4MAPK1ALDH1A1BCHE
SCHEMBL11045804 0.89 ALDH1A1 (0.38) TSHRCYP3A4MAPK1ALDH1A1BCHE
SCHEMBL29366549 0.89 TSHR (0.47) TSHRCYP3A4MAPK1ALDH1A1BCHE
SCHEMBL120851 0.88 ALDH1A1 (0.42) TSHRCYP3A4MAPK1ALDH1A1BCHE
SCHEMBL1199708 0.81 CYP3A4 (0.63) TSHRCYP3A4MAPK1ALDH1A1BCHE
SCHEMBL31387618 0.81 CYP3A4 (0.63) TSHRCYP3A4MAPK1ALDH1A1BCHE
SCHEMBL31606803 0.79 ESR1 (0.43) TSHRCYP3A4MAPK1ALDH1A1BCHE
SCHEMBL120843 0.79 BCHE (0.37) TSHRCYP3A4MAPK1ALDH1A1BCHE
SCHEMBL13145957 0.78 BCHE (0.33) TSHRCYP3A4MAPK1ALDH1A1BCHE
SCHEMBL13969657 0.78 POLB (0.37) TSHRALDH1A1BCHECES1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118978422-A Chiral ring [8] m-benzene macrocyclic compound and synthesis method thereof 淮南师范学院 2024-11-19 CN claimed
CN-115819437-A 4-bromobenzo [1,2-b:3,4-b' ] dithiophene-2,7-dialdehyde and preparation method and application thereof 青岛农业大学 2023-03-21 CN claimed
CN-114560869-A 4-bromobenzo [1,2-b:3,4-b' ] dithiophene-2, 7-dimethyl aldehyde and preparation method thereof 青岛农业大学 2022-05-31 CN claimed
US-20260053393-A1 NEAR-IR GLUCOSE SENSORS PROFUSA INC (US) 2026-02-26 US disclosed
US-20250230174-A1 NEAR-IR GLUCOSE SENSORS PROFUSA, INC. (US) 2025-07-17 US disclosed
US-12285250-B2 Near-IR glucose sensors PROFUSA, INC (US) 2025-04-29 US disclosed
WO-2025085560-A1 LYSINE ACETYLTRANSFERASE INHIBITORS Kronos Bio, Inc. (US) 2025-04-24 WO disclosed
CN-118978422-B Chiral ring [8] m-benzene macrocyclic compound and synthesis method thereof 淮南师范学院 2025-01-28 CN disclosed
CN-118978422-A Chiral ring [8] m-benzene macrocyclic compound and synthesis method thereof 淮南师范学院 2024-11-19 CN disclosed
US-20240190805-A1 PHENYLACETIC ACID DERIVATIVE, USE THEREFOR, AND PRODUCTION INTERMEDIATE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-06-13 US disclosed
CN-115819437-B 4-Bromobenzo [1,2-b:3,4-b' ] dithiophene-2, 7-dicarboxaldehyde and preparation method and application thereof 青岛农业大学 2024-06-04 CN disclosed
US-20070210699-A1 Metal complex compound and organic electroluminescence device using the compound CHUO UNIVERSITY (JP) 2007-09-13 US disclosed
US-20070210699-A1 Metal complex compound and organic electroluminescence device using the compound CHUO UNIVERSITY (JP) 2007-09-13 US disclosed
US-20070197751-A1 Olefin polymerization catalyst system useful for polar monomers EXXONMOBIL CHEMICAL PATENTS INC. 2007-08-23 US disclosed
US-20070197751-A1 Olefin polymerization catalyst system useful for polar monomers EXXONMOBIL CHEMICAL PATENTS INC. 2007-08-23 US disclosed
EP-1816134-A1 METAL COMPLEX COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-08-08 EP disclosed
US-20070065360-A1 Nonpolar thymidine analogs NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-03-22 US disclosed
US-4752642-A Ethynyl-containing aromatic polyamide resin THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1988-06-21 US disclosed
US-4663425-A LAMINATION, FABRICS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1987-05-05 US disclosed
US-4657708-A AROMATIC POLYAMIDE RESINS CYCLIZED INTO POLYIMIDINES WITHOUT EVOLUTION OF VOLATILES; LAMINATES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1987-04-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250230174-A1 NEAR-IR GLUCOSE SENSORS IRS1, INSR, SLC2A4 TSHR 890/4885CYP3A4 3223/4885MAPK1 1969/4885
US-20260053393-A1 NEAR-IR GLUCOSE SENSORS INSR, IRS1, SLC2A4 TSHR 162/4885CYP3A4 1269/4885MAPK1 520/4885
US-20070210699-A1 Metal complex compound and organic electroluminescence device using the compound EMC2, LAGE3, EPCAM TSHR 3430/4885CYP3A4 1542/4885MAPK1 2803/4885
US-20240190805-A1 PHENYLACETIC ACID DERIVATIVE, USE THEREFOR, AND PRODUCTION INTERMEDIATE THEREOF FAR1, CYP4A11, CYP4F11 TSHR 1946/4885CYP3A4 63/4885MAPK1 504/4885
US-20070065360-A1 Nonpolar thymidine analogs TK1, TYMP, TK2 TSHR 56/4885CYP3A4 2619/4885MAPK1 1250/4885
US-12285250-B2 Near-IR glucose sensors IRS1, SLC2A4, GPR119 TSHR 1126/4885CYP3A4 571/4885MAPK1 664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.