Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | RHOA | P61586 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11336915 | 0.81 | TDP1 (0.35) | CYP3A4ALDH1A1HSD17B10TSHRKMT2A | |
| SCHEMBL7626169 | 0.80 | CYP3A4 (0.42) | CYP3A4ALDH1A1HSD17B10TSHRRHOA | |
| SCHEMBL9421001 | 0.80 | THRB (0.53) | CYP3A4ALDH1A1HSD17B10TSHRMAPK1 | |
| SCHEMBL3716825 | 0.79 | TDP1 (0.36) | CYP3A4ALDH1A1TSHRKMT2ALMNA | |
| SCHEMBL129333 | 0.77 | TSHR (0.55) | CYP3A4ALDH1A1HSD17B10TSHRNPSR1 | |
| SCHEMBL2443804 | 0.76 | TDP1 (0.59) | CYP3A4ALDH1A1TSHRKMT2AMAPT | |
| SCHEMBL8673620 | 0.76 | TSHR (0.53) | CYP3A4ALDH1A1HSD17B10TSHRNPSR1 | |
| SCHEMBL11414429 | 0.75 | KDM4E (0.50) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL130905 | 0.75 | ALDH1A1 (0.58) | CYP3A4ALDH1A1HSD17B10TSHRMEN1 | |
| SCHEMBL16371573 | 0.74 | CYP3A4 (1.00) | CYP3A4ALDH1A1HSD17B10TSHRRHOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 662 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099156-A1 | Heterocyclic Compounds as Ccr2b antagonists | ASTRAZENECA AB (SE) | 2009-04-16 | — | — | US | claimed |
| CN-100344613-C | Preparatino method of (2S,4S)-1-(4-nitro carbobenzoyl)-2-[(3-allyloxycarbonyl)-phenyl aminoformyl]-pyrrolidine -4-thioalcohol | UNIV SHANGHAI JIAOTONG (CN) | 2007-10-24 | — | — | CN | claimed |
| EP-1831164-A1 | HETEROCYCLIC COMPOUNDS AS CCR2B ANTAGONISTS | AstraZeneca AB (SE) | 2007-09-12 | — | — | EP | claimed |
| US-20060211626-A1 | For treating preterm labor and dysmenorrhea | THERATECHNOLOGIES, INC. (CA) | 2006-09-21 | — | — | US | claimed |
| WO-2006067401-A1 | HETEROCYCLIC COMPOUNDS AS CCR2B ANTAGONISTS | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | WO | claimed |
| CN-1752073-A | Preparatino method of (2S,4S)-1-(4-nitro carbobenzoyl)-2-[(3-allyloxycarbonyl)-phenyl aminoformyl]-pyrrolidine -4-thioalcohol | UNIV SHANGHAI JIAOTONG (CN) | 2006-03-29 | — | — | CN | claimed |
| EP-1511764-A2 | PEPTIDES AND PEPTIDOMIMETICS USEFUL FOR INHIBITING THE ACTIVITY OF PROSTAGLANDIN F sb 2a /sb RECEPTOR | THERATECHNOLOGIES INC. (CA) | 2005-03-09 | — | — | EP | claimed |
| EP-0879231-B1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | UNIV VANDERBILT (US) | 2004-09-22 | — | — | EP | claimed |
| WO-2003104266-A2 | PEPTIDES AND PEPTIDOMIMETICS USEFUL FOR INHIBITING THE ACTIVITY OF PROSTAGLANDIN F2α RECEPTOR | THERATECHNOLOGIES INC. (CA) | 2003-12-18 | — | — | WO | claimed |
| US-6262098-B1 | ISOXAZOLE ESTROGEN RECEPTOR AGONIST AND ANTAGONIST | CHIRON CORPORATION | 2001-07-17 | — | — | US | claimed |
| WO-2023214017-A1 | CYCLIC CIDOFOVIR OR A PRODRUG THEREOF FOR USE IN THE TREATMENT OR PREVENTION OF AFRICAN SWINE FEVER | VIROVET NV (BE) | 2023-11-09 | — | — | WO | disclosed |
| CN-110446739-B | Fluoroacetophenone-containing derivative, fluorine-containing additive, curable composition containing the same, and cured product thereof | DIC株式会社 | 2022-01-11 | — | — | CN | disclosed |
| US-10961405-B2 | Fluorine-containing acetophenone derivative, fluroine based additive, curable composition including same, and cured product thereof | DIC CORPORATION (JP) | 2021-03-30 | — | — | US | disclosed |
| US-10852236-B2 | Method of measuring plant nutrient transport using near-infrared imaging | Curadel, LLC (US) | 2020-12-01 | — | — | US | disclosed |
| CN-111954849-A | Photosensitive resin composition, cured product, insulating material, resin material for solder resist, and resist member | DIC株式会社 | 2020-11-17 | — | — | CN | disclosed |
| WO-1996007651-A1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1996-03-14 | — | — | WO | disclosed |
| WO-1996003396-A1 | DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1996-02-08 | — | — | WO | disclosed |
| US-4845094-A | HYPOGLYCEMIC, ANTICOAGULANT | SUNTORY LIMITED (JP) | 1989-07-04 | — | — | US | disclosed |
| US-4720500-A | N-1,8-naphthyridin-2-yl amides useful as immunostimulants | RHONE-POULENC SANTE (FR) | 1988-01-19 | — | — | US | disclosed |
| EP-0250265-A1 | 2-Phenylbenzoxepin derivative | SUNTORY LIMITED (JP) | 1987-12-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211626-A1 | For treating preterm labor and dysmenorrhea | PGF, PTGFR, PTGER1 | CYP3A4 2390/4885ALDH1A1 2607/4885HSD17B10 1635/4885 |
| US-20090099156-A1 | Heterocyclic Compounds as Ccr2b antagonists | CCR2, CCR3, CXCR2 | CYP3A4 1686/4885ALDH1A1 3415/4885HSD17B10 2846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.