Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nonane SCHEMBL10388435 | 1.00 | TSHR (0.58) | TSHRSMN1; SMN2NAAASIGMAR1DNM1 | |
| Chlorobenzene SCHEMBL2952823 | 0.97 | TSHR (0.61) | TSHRSMN1; SMN2NAAASIGMAR1DNM1 | |
| Chlorobenzene SCHEMBL27347602 | 0.95 | TSHR (0.58) | TSHRSMN1; SMN2NAAASIGMAR1DNM1 | |
| Chlorobenzene SCHEMBL19332300 | 0.92 | TSHR (0.61) | TSHRSMN1; SMN2NAAASIGMAR1TP53 | |
| Chlorobenzene SCHEMBL11251710 | 0.91 | TSHR (0.56) | TSHRSMN1; SMN2NAAASIGMAR1DNM1 | |
| Chlorobenzene SCHEMBL28460320 | 0.89 | DNM1 (0.54) | TSHRSMN1; SMN2DNM1EPHX1ALDH1A1 | |
| Octanol SCHEMBL6839224 | 0.89 | LMNA (0.54) | TSHRSMN1; SMN2NAAAEPHX1ALDH1A1 | |
| Octadecylamine SCHEMBL28143508 | 0.89 | DNM1 (0.54) | TSHRSMN1; SMN2DNM1EPHX1ALDH1A1 | |
| 1-Hexanol SCHEMBL5309008 | 0.89 | LMNA (0.54) | TSHRSMN1; SMN2NAAAEPHX1ALDH1A1 | |
| Chlorobenzene SCHEMBL27309000 | 0.89 | DNM1 (0.54) | TSHRSMN1; SMN2DNM1EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024063116-A1 | ORGANIC LIGHT-EMITTING ELEMENT | キヤノン株式会社 | 2024-03-28 | — | — | WO | disclosed |
| US-20220177476-A1 | Crystal Forms of (S)-4-(8-amino-3-(1-(but-2-ynoyl)-pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-n-(pyridin-2-yl)benzamide | ACERTA PHARMA BV (NL) | 2022-06-09 | — | — | US | disclosed |
| US-10640509-B2 | Pharmaceutical composition comprising a crystal form of (S)-4-(8-amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide for treating diffuse large B-cell lymphoma | ACERTA PHARMA B.V. (NL) | 2020-05-05 | — | — | US | disclosed |
| US-20190337949-A1 | Solid Forms and Formulations of Imidazopyrazine Compound | ACERTA PHARMA B.V. (NL) | 2019-11-07 | — | — | US | disclosed |
| US-9796721-B2 | Crystal forms of (S)-4-(8-amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide | ACERTA PHARMA B.V. (NL) | 2017-10-24 | — | — | US | disclosed |
| US-20170029428-A1 | Solid Forms and Formulations of Imidazopyrazine Compound | ACERTA PHARMA B.V. (NL) | 2017-02-02 | — | — | US | disclosed |
| US-7375250-B2 | Aminoanthryl derivative substitution compound and organic electroluminescence device using the same | CANON KABUSHIKI KAISHA (JP) | 2008-05-20 | — | — | US | disclosed |
| US-7358409-B2 | Substituted anthryl derivative and electroluminescence device using the same | CANON KABUSHIKI KAISHA (JP) | 2008-04-15 | — | — | US | disclosed |
| US-7309533-B2 | Substituted anthryl derivative and electroluminescence device using the same | CANON KABUSHIKI KAISHA (JP) | 2007-12-18 | — | — | US | disclosed |
| US-7173131-B2 | Anthryl derivative group substituted compound, and organic luminescent device making use of same | CANON KABUSHIKI KAISHA (JP) | 2007-02-06 | — | — | US | disclosed |
| US-7129386-B2 | Substituted anthryl derivative and electroluminescence device using the same | CANON KABUSHIKI KAISHA (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20060125378-A1 | Aminoanthryl derivative substitution compound and organic electroluminescence device using the same | CANON KABUSHIKI KAISHA (JP) | 2006-06-15 | — | — | US | disclosed |
| US-20050099115-A1 | Substituted anthryl derivative and electoluminescence device using the same | CANON KABUSHIKI KAISHA (JP) | 2005-05-12 | — | — | US | disclosed |
| US-20040263067-A1 | Anthryl derivative group substituted compound, and organic luminescent device making use of same | CANON KABUSHIKI KAISHA (JP) | 2004-12-30 | — | — | US | disclosed |
| EP-0179953-B1 | MOLDING COMPOSITION | ARCO CHEMICAL TECHNOLOGY, INC. (US) | 1989-08-23 | — | — | EP | disclosed |
| EP-0134026-B1 | A METHOD OF MANUFACTURING A MACROMOLECULAR MATERIAL CONDUCTING CURRENT ON ITS SURFACE | POLSKA AKADEMIA NAUK CENTRUMBADAN MOLEKULARNYCH I MAKROMOLEKULARNYCH (PL) | 1987-10-14 | — | — | EP | disclosed |
| EP-0179953-A1 | Molding composition | ARCO CHEMICAL TECHNOLOGY, INC. (US) | 1986-05-07 | — | — | EP | disclosed |
| US-4485215-A | EPDM RUBBER, OLEFIN-ACRYLATE COPOLYMER, AROMATIC-NITRILE- MALEIMIDE TERPOLYMER | ATLANTIC RICHFIELD COMPANY (US) | 1984-11-27 | — | — | US | disclosed |
| US-4483966-A | CATALYTIC VAPOR PHASE POLYMERIZATION WITH COORIDNATION CATALYST | CHISSO CORPORATION (JP) | 1984-11-20 | — | — | US | disclosed |
| EP-0021822-A1 | Titanium trichloride catalytic component and method for homo- or co-polymerization of alpha-olefins | TOYO STAUFFER CHEMICAL CO. LTD. (JP) | 1981-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177476-A1 | Crystal Forms of (S)-4-(8-amino-3-(1-(but-2-ynoyl)-pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-n-(pyridin-2-yl)benzamide | ALB, NPY5R, PGA5 | TSHR 3297/4885SMN1; SMN2 1166/4885NAAA 580/4885 |
| US-10640509-B2 | Pharmaceutical composition comprising a crystal form of (S)-4-(8-amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide for treating diffuse large B-cell lymphoma | MALT1, BCL6, BCL3 | TSHR 3654/4885SMN1; SMN2 1580/4885NAAA 1664/4885 |
| US-20190337949-A1 | Solid Forms and Formulations of Imidazopyrazine Compound | SLC5A2, IL5, NPY5R | TSHR 3399/4885SMN1; SMN2 550/4885NAAA 1554/4885 |
| US-20060125378-A1 | Aminoanthryl derivative substitution compound and organic electroluminescence device using the same | ALAD, TYR, DDC | TSHR 4020/4885SMN1; SMN2 4350/4885NAAA 724/4885 |
| US-20170029428-A1 | Solid Forms and Formulations of Imidazopyrazine Compound | SLC5A2, IL5, NPY5R | TSHR 3399/4885SMN1; SMN2 550/4885NAAA 1554/4885 |
| US-20050099115-A1 | Substituted anthryl derivative and electoluminescence device using the same | ALAD, ERAL1, LAGE3 | TSHR 2029/4885SMN1; SMN2 3545/4885NAAA 222/4885 |
| US-20040263067-A1 | Anthryl derivative group substituted compound, and organic luminescent device making use of same | ALAD, AAAS, NLRP1 | TSHR 4384/4885SMN1; SMN2 4478/4885NAAA 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.