Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 5/20 | 0.50 |
| ▸ | PPARD | Q03181 | 5/20 | 0.50 |
| ▸ | PPARA | Q07869 | 5/20 | 0.50 |
| ▸ | F7 | P08709 | 4/20 | 0.50 |
| ▸ | F3 | P13726 | 4/20 | 0.50 |
| ▸ | TERT | O14746 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | TOP1 | P11387 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | FABP4 | P15090 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.50 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dectaflur SCHEMBL4829779 | 0.84 | SLC6A5 (0.53) | PPARGPPARDPPARAF7F3 | |
| Oleamide SCHEMBL4829765 | 0.82 | FAAH (0.68) | PPARGPPARDPPARAF7F3 | |
| Methyl Oleate SCHEMBL31357318 | 0.79 | EPHX2 (0.56) | PPARGPPARDPPARAF7F3 | |
| Methyl Oleate SCHEMBL30049475 | 0.79 | EPHX2 (0.56) | PPARGPPARDPPARAF7F3 | |
| Potassium Ion SCHEMBL4829969 | 0.78 | FABP3 (0.54) | HSD17B10FABP4MAPTBLMLMNA | |
| SCHEMBL18955451 | 0.76 | ACE2 (0.65) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL6432220 | 0.76 | ACE2 (0.65) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL3087851 | 0.76 | TERT (0.56) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL22772992 | 0.76 | ACE2 (0.65) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL1647192 | 0.76 | ACE2 (0.65) | PPARGPPARDPPARAF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410934-B2 | Aqueous viscoelastic fluid | SCHLUMBERGER TECHNOLOGY CORPORATION (US) | 2008-08-12 | — | — | US | disclosed |
| US-20040094301-A1 | Aqueous viscoelastic fluid | SCHLUMBERGER TECHNOLOGY CORPORATION | 2004-05-20 | — | — | US | disclosed |
| WO-2002064947-A1 | AQUEOUS VISCOELASTIC FLUID | SOFITECH N.V. (BE) | 2002-08-22 | — | — | WO | disclosed |