SCHEMBL4831796

SCHEMBL4831796

COc1ccc(S(=O)(=O)ON2C(=O)C3C4C=CC(C3C2=O)C2C(=O)N(OS(=O)(=O)c3ccc(OC)cc3)C(=O)C42)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.45
PKM P14618 3/20 0.43
MMP2 P08253 3/20 0.41
NPC1 O15118 1/20 0.41
PKLR P30613 1/20 0.41
RAB9A P51151 1/20 0.41
VDR P11473 1/20 0.40
MMP9 P14780 2/20 0.40
EP300 Q09472 1/20 0.40
KAT2A Q92830 1/20 0.40
KAT2B Q92831 1/20 0.40
HTT P42858 2/20 0.39
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4835021 0.91 GAA (0.49) GAAPKMMMP2NPC1PKLR
SCHEMBL4835774 0.85 VDR (0.56) GAAPKMMMP2VDRHTT
SCHEMBL13473215 0.85 ALDH1A1 (0.51) GAAMMP2NPC1RAB9AHTT
SCHEMBL4834882 0.82 LMNA (0.49) GAAPKMHTTLMNASMN1; SMN2
SCHEMBL4827225 0.81 PARL (0.57) NPC1RAB9AVDRHTTLMNA
SCHEMBL4887014 0.81 ALDH1A1 (0.58) VDRHTTLMNASMN1; SMN2L3MBTL1
SCHEMBL4826503 0.81 GAA (0.49) GAAPKMMMP2NPC1PKLR
SCHEMBL4835027 0.78 TDP1 (0.40) PKMVDRHTTLMNATDP1
SCHEMBL6420670 0.78 KMT2A (0.39) VDRALDH1A1CA1CA2PTGS2
SCHEMBL65074 0.76 GAA (0.66) GAAPKMMMP2NPC1PKLR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7374857-B2 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2008-05-20 US disclosed
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2005-02-17 US disclosed
EP-1449833-A1 BISIMIDE COMPOUND, ACID GENERATOR AND RESIST COMPOSITION EACH CONTAINING THE SAME, AND METHOD OF FORMING PATTERN FROM THE COMPOSITION Wako Pure Chemical Industries, Ltd. (JP) 2004-08-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition ASIC1, GAR1, RER1 GAA 2435/4885PKM 2549/4885MMP2 4856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.