Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GALK1 | P51570 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685337 | 0.78 | KDM1A (0.42) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL5999291 | 0.78 | ALDH1A1 (0.40) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL8606301 | 0.76 | DNMT1 (0.41) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL8966049 | 0.75 | ESR1 (0.41) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL7927537 | 0.75 | GSTP1 (0.43) | ALDH1A1TSHRKDM4EMAPTHIF1A | |
| Hydrochloric Acid SCHEMBL540484 | 0.75 | GPR3 (0.44) | CYP1A2CYP2D6MEN1KMT2A | |
| SCHEMBL9123563 | 0.74 | HDAC3 (0.36) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL24023063 | 0.73 | KDM1A (0.38) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL7944464 | 0.73 | GPR3 (0.42) | CYP1A2CYP2D6MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7270000 | 0.72 | GPR3 (0.36) | ALDH1A1TSHRKDM4ENPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12612529-B2 | Ethylene/alpha-olefin copolymer composition and application thereof | MITSUI CHEMICALS, INC. (JP) | 2026-04-28 | — | — | US | disclosed |
| EP-4685217-A1 | AQUEOUS LUBRICANT COMPOSITION | Mitsui Chemicals, Inc. (JP) | 2026-01-28 | — | — | EP | disclosed |
| US-20250197621-A1 | THERMOPLASTIC RESIN COMPOSITION | MITSUI CHEMICALS, INC. (JP) | 2025-06-19 | — | — | US | disclosed |
| EP-4495182-A1 | THERMOPLASTIC RESIN COMPOSITION | Mitsui Chemicals, Inc. (JP) | 2025-01-22 | — | — | EP | disclosed |
| US-20240352253-A1 | RESIN COMPOSITION AND USE THEREOF | MITSUI CHEMICALS, INC. (JP) | 2024-10-24 | — | — | US | disclosed |
| WO-2024204149-A1 | ADHESIVE COMPOSITION AND METHOD FOR PRODUCING SAME, AND ADHESIVE SHEET | 三井化学株式会社 | 2024-10-03 | — | — | WO | disclosed |
| WO-2024195445-A1 | AQUEOUS LUBRICANT COMPOSITION | 三井化学株式会社 | 2024-09-26 | — | — | WO | disclosed |
| EP-4435047-A1 | RESIN COMPOSITION AND USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2024-09-25 | — | — | EP | disclosed |
| US-20240263051-A1 | RESIN COMPOSITION, USE THEREOF, AND METHOD FOR PRODUCING SAME | MITSUI CHEMICALS, INC. (JP) | 2024-08-08 | — | — | US | disclosed |
| EP-3950893-B1 | LUBRICATING OIL COMPOSITION FOR INDUSTRIAL GEARS AND METHOD FOR PRODUCING SAME | MITSUI CHEMICALS INC (JP) | 2024-07-17 | — | — | EP | disclosed |
| EP-2511305-A1 | Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same | Mitsui Chemicals, Inc. (JP) | 2012-10-17 | — | — | EP | disclosed |
| EP-2465878-A1 | Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same | Mitsui Chemicals, Inc. (JP) | 2012-06-20 | — | — | EP | disclosed |
| EP-2465879-A1 | Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same | Mitsui Chemicals, Inc. (JP) | 2012-06-20 | — | — | EP | disclosed |
| US-7452946-B2 | copolymer with C3 to C10 alpha -olefin; provides a blow-molded product and an extrusion-molded product excellent in moldability, mechanical strength and outward appearance; produced in the presence of a solid catalyst | MITSUI CHEMICALS, INC. (JP) | 2008-11-18 | — | — | US | disclosed |
| US-20060199925-A1 | Ethylene polymer | MITSUI CHEMICALS, INC. (JP) | 2006-09-07 | — | — | US | disclosed |
| CN-1791619-A | Ethylene polymer | MITSUI CHEMICALS INC (JP) | 2006-06-21 | — | — | CN | disclosed |
| CN-1782044-A | Synthetic lubricating oil and lubricating oil composition | MITSUI CHEMICALS INC (JP) | 2006-06-07 | — | — | CN | disclosed |
| EP-1661921-A1 | Synthetic lubricating oil and lubricating oil composition thereof | Mitsui Chemicals, Inc. (JP) | 2006-05-31 | — | — | EP | disclosed |
| EP-1632505-A1 | ETHYLENE POLYMER | Mitsui Chemicals, Inc. (JP) | 2006-03-08 | — | — | EP | disclosed |
| EP-1548018-A1 | CROSSLINKED METALLOCENE COMPOUND FOR OLEFIN POLYMERIZATION AND METHOD OF POLYMERIZING OLEFIN WITH THE SAME | Mitsui Chemicals, Inc. (JP) | 2005-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12612529-B2 | Ethylene/alpha-olefin copolymer composition and application thereof | ELOVL1, EEF1D, EEF1G | ALDH1A1 815/4885HSD17B10 621/4885CYP2A6 2695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.