SCHEMBL3580327

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17622509	0.88	GAA (0.42)	GAAAKR1B1CA2CXCL8CAMK2A
	SCHEMBL5357198	0.83	AKR1B1 (0.40)	GAAAKR1B1CA2CXCL8CAMK2A
	SCHEMBL4837065	0.83	AKR1B1 (0.45)	AKR1B1CA2CXCL8CAMK2ACYP2C9
	SCHEMBL4549702	0.79	GAA (0.53)	GAACXCL8CHRM1
	SCHEMBL7714917	0.79	GAA (0.54)	GAACYP2C9
	SCHEMBL19181631	0.78	SIGMAR1 (0.43)	GAACYP2C9SLC9A1
	SCHEMBL14793743	0.78	CA2 (0.53)	GAAAKR1B1CA2CXCL8CAMK2A
	SCHEMBL7164323	0.76	ABCB11 (0.40)	AKR1B1CA2CXCL8CAMK2ACYP2C9
	SCHEMBL72627	0.75	SMN1; SMN2 (0.41)	GAACYP2C9
	SCHEMBL11164004	0.75	CA2 (0.50)	GAAAKR1B1CA2CXCL8CAMK2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.