Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
| ▸ | GIPR | P48546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4839632 | 0.74 | CSNK2A1 (0.32) | CSNK2A1TRPV3 | |
| SCHEMBL4776899 | 0.74 | MEN1 (0.37) | CSNK2A1TRPV3GCGRGIPR | |
| SCHEMBL5569939 | 0.70 | CSNK2A1 (0.33) | FAAHCSNK2A1TRPV3GCGRGIPR | |
| SCHEMBL4718876 | 0.67 | CENPE (0.36) | GCGRGIPR | |
| SCHEMBL4717681 | 0.65 | CENPE (0.36) | GCGRGIPR | |
| SCHEMBL2617238 | 0.64 | TAS1R3 (0.43) | GCGRGIPR | |
| SCHEMBL4722601 | 0.63 | GCGR (0.43) | CSNK2A1GCGRGIPR | |
| SCHEMBL5569669 | 0.63 | CSNK2A1 (0.57) | CSNK2A1 | |
| SCHEMBL5568781 | 0.59 | S1PR1 (0.34) | CSNK2A1 | |
| SCHEMBL13637058 | 0.58 | TAS1R3 (0.43) | CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942732-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-07-16 | — | — | EP | claimed |
| WO-2007056143-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-18 | — | — | WO | claimed |