Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 2/20 | 0.37 |
| ▸ | GIPR | P48546 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5569474 | 0.81 | P2RX3 (0.39) | MEN1KMT2AGCGRGIPRP2RX3 | |
| SCHEMBL4880126 | 0.74 | FAAH (0.32) | GCGRGIPRTRPV3CSNK2A1 | |
| SCHEMBL4839632 | 0.74 | CSNK2A1 (0.32) | TRPV3CSNK2A1 | |
| SCHEMBL4718281 | 0.70 | CENPE (0.36) | GCGRGIPRPPARGMMEMMEL1 | |
| SCHEMBL5569467 | 0.69 | CENPE (0.39) | MEN1KMT2AP2RX3PPARGPPARA | |
| SCHEMBL4718876 | 0.69 | CENPE (0.36) | GCGRGIPRPPARG | |
| SCHEMBL4717681 | 0.69 | CENPE (0.36) | GCGRGIPRPPARGMMEMMEL1 | |
| SCHEMBL5569135 | 0.69 | MEN1 (0.36) | MEN1KMT2AGCGRGIPRP2RX3 | |
| SCHEMBL2617238 | 0.68 | TAS1R3 (0.43) | GCGRGIPRPPARG | |
| SCHEMBL4876587 | 0.68 | S1PR1 (0.39) | MEN1KMT2AP2RX3MMEMMEL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942732-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-07-16 | — | — | EP | claimed |
| WO-2007056143-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-18 | — | — | WO | claimed |
| EP-1942732-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007056143-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-18 | — | — | WO | disclosed |