Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4841559 | 1.00 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1AKR1B1L3MBTL1RAB9A | |
| SCHEMBL4843078 | 0.95 | L3MBTL1 (0.42) | CYSLTR2CYSLTR1AKR1B1L3MBTL1RAB9A | |
| SCHEMBL4843067 | 0.95 | L3MBTL1 (0.42) | CYSLTR2CYSLTR1AKR1B1L3MBTL1RAB9A | |
| SCHEMBL4575361 | 0.79 | FBP1 (0.44) | L3MBTL1KMT2ANR1H3KDM4EALDH1A1 | |
| SCHEMBL4575360 | 0.79 | FBP1 (0.44) | L3MBTL1KMT2ANR1H3KDM4EALDH1A1 | |
| SCHEMBL6313868 | 0.79 | MAOA (0.46) | CYSLTR2CYSLTR1RAB9ATDP1TLR4 | |
| SCHEMBL4840291 | 0.77 | RAB9A (0.50) | L3MBTL1RAB9AKMT2ATDP1ALDH1A1 | |
| SCHEMBL29451792 | 0.76 | HSD17B10 (0.41) | RAB9AKMT2ATDP1NR1H3ALDH1A1 | |
| SCHEMBL6779922 | 0.75 | PPARG (0.54) | NR1H3 | |
| SCHEMBL6779926 | 0.75 | PPARG (0.54) | NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465811-B2 | Indoline compounds | LABORATOIRES FOURNIER S.A. (FR) | 2008-12-16 | — | — | US | disclosed |
| US-20080119465-A1 | Novel Indoline Compounds | LABORATORIES FOURNIER S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119465-A1 | Novel Indoline Compounds | GPR119, INSR, IRS1 | CYSLTR2 2201/4885CYSLTR1 1117/4885AKR1B1 503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.