Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL484030 | 0.86 | — | — | |
| SCHEMBL10395196 | 0.80 | — | — | |
| SCHEMBL301410 | 0.80 | ALDH1A1 (0.42) | ALDH1A1ALOX15 | |
| SCHEMBL5573217 | 0.78 | GABRP (0.33) | MIFABCB11ALDH1A1NR3C1CYP1A2 | |
| SCHEMBL10509802 | 0.74 | APLNR (0.35) | MIFALDH1A1 | |
| SCHEMBL28639157 | 0.71 | — | — | |
| SCHEMBL24566815 | 0.68 | — | — | |
| SCHEMBL10682103 | 0.67 | — | — | |
| SCHEMBL125198 | 0.54 | GABRA1 (0.34) | MIF | |
| SCHEMBL16707452 | 0.54 | GABRA1 (0.39) | MIFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3779531-B1 | PHOTOCHROMIC OPTICAL ARTICLE AND METHOD FOR MANUFACTURING SAME | TOKUYAMA CORP (JP) | 2024-03-20 | — | — | EP | disclosed |
| US-11767467-B2 | Photochromic compound and curable composition containing said photochromic compound | TOKUYAMA CORPORATION (JP) | 2023-09-26 | — | — | US | disclosed |
| EP-3345954-B1 | POLYROTAXANE, PRODUCTION METHOD THEREFOR, AND OPTICAL COMPOSITION CONTAINING SAID POLYROTAXANE | TOKUYAMA CORP (JP) | 2023-07-05 | — | — | EP | disclosed |
| US-20230120549-A1 | Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same | PPG INDUSTRIES OHIO, INC. | 2023-04-20 | — | — | US | disclosed |
| EP-3653615-B1 | CHROMENE COMPOUND, CURABLE COMPOSITION COMPRISING SAME, AND OPTICAL ARTICLE COMPRISING CURED PRODUCT FORMED OF CURABLE COMPOSITION | TOKUYAMA CORP (JP) | 2023-03-01 | — | — | EP | disclosed |
| US-11578174-B2 | Polyrotaxane, production method therefor, and optical composition containing said polyrotaxane | TOKUYAMA CORPORATION (JP) | 2023-02-14 | — | — | US | disclosed |
| US-11472912-B2 | Polyurethanes, articles and coatings prepared therefrom and methods of making the same | PPG INDUSTRIES OHIO, INC. (US) | 2022-10-18 | — | — | US | disclosed |
| US-11401276-B2 | Chromene compound, curable composition comprising the compound, and optical article including a cured body of the curable composition | TOKUYAMA CORPORATION (JP) | 2022-08-02 | — | — | US | disclosed |
| CN-110799573-B | Photochromic polyrotaxane compound, and curable composition comprising same | 株式会社德山 | 2022-06-03 | — | — | CN | disclosed |
| US-20220162486-A1 | PHOTOCHROMIC OPTICAL ARTICLE AND METHOD FOR MANUFACTURING SAME | TOKUYAMA CORPORATION (JP) | 2022-05-26 | — | — | US | disclosed |
| EP-0351073-B1 | Lens comprising a resin having a large refractive index and process for preparing the lens | MITSUI TOATSU CHEMICALS (JP) | 1994-09-21 | — | — | EP | disclosed |
| US-5283312-A | Colorless, transparent, high refractive index, heat resistance, low dispersion; polythiourethanes | MITSUI TOATSU CHEMICALS, INC. (JP) | 1994-02-01 | — | — | US | disclosed |
| EP-0378895-B1 | A MERCAPTO COMPOUND, A HIGH REFRACTIVE INDEX RESIN AND LENS AND A PROCESS FOR PREPARING THEM | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-07-14 | — | — | EP | disclosed |
| EP-0549808-A1 | TRANSPARENT PLASTIC MATERIAL | SEIKO EPSON CORPORATION (JP) | 1993-07-07 | — | — | EP | disclosed |
| US-5191055-A | Polythiourethanes | MITSUI TOATSU CHEMICALS, INC. (JP) | 1993-03-02 | — | — | US | disclosed |
| EP-0528590-A1 | Mercapto compound, its preparation process, and sulfur-containing urethane resins and lenses using the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-02-24 | — | — | EP | disclosed |
| US-5087758-A | Polythiourethane monomer | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-02-11 | — | — | US | disclosed |
| US-5084545-A | Polythiourethanes for impact strength, lightweight lenses | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0378895-A1 | A mercapto compound, a high refractive index resin and lens and a process for preparing them | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-07-25 | — | — | EP | disclosed |
| EP-0351073-A2 | Lens comprising a resin having a large refractive index and process for preparing the lens | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-01-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11401276-B2 | Chromene compound, curable composition comprising the compound, and optical article including a cured body of the curable composition | INCENP, SMCHD1, ILK | MIF 276/4885ABCB11 4355/4885ALDH1A1 2274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.