Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5258292 | 0.91 | RAB9A (0.42) | FFAR1RAB9AGFERSMN1; SMN2FABP4 | |
| Trifluoroacetic Acid SCHEMBL4844143 | 0.87 | ABL1 (0.49) | HDAC3HDAC1HDAC2HDAC6PTK2 | |
| Trifluoroacetic Acid SCHEMBL4845670 | 0.85 | FFAR1 (0.42) | FFAR1FABP4HDAC1KDR | |
| Trifluoroacetic Acid SCHEMBL4839090 | 0.85 | GPR6 (0.43) | FFAR1FABP4HDAC3HDAC1HDAC2 | |
| Trifluoroacetic Acid SCHEMBL4845402 | 0.84 | MEN1 (0.39) | KMT2A | |
| Trifluoroacetic Acid SCHEMBL4843358 | 0.82 | ABL1 (0.44) | RAB9ASMN1; SMN2HDAC3HDAC1HDAC2 | |
| Trifluoroacetic Acid SCHEMBL4843563 | 0.82 | ALDH1A1 (0.41) | RAB9ASMN1; SMN2MMP2MMP9MMP8 | |
| Trifluoroacetic Acid SCHEMBL5259763 | 0.82 | MMP2 (0.35) | FFAR1RAB9ASMN1; SMN2HDAC6MMP2 | |
| Trifluoroacetic Acid SCHEMBL4841657 | 0.81 | TAAR1 (0.41) | RAB9AHDAC1HDAC6MMP2MMP9 | |
| Trifluoroacetic Acid SCHEMBL4838725 | 0.81 | MMP2 (0.34) | FFAR1RAB9ASMN1; SMN2HDAC6MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410966-B2 | Use of and some novel imidazopyridines | ASTRAZENECA AB (SE) | 2008-08-12 | — | — | US | disclosed |
| US-20050261333-A1 | Use of and some novel imidazopyridines | ASTRAZENECA A B (SE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261333-A1 | Use of and some novel imidazopyridines | ITK, CSNK1A1, RPS6KA1 | FFAR1 1301/4885RAB9A 1616/4885GFER 4150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.