Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.40 |
| ▸ | TTR | P02766 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1137323 | 0.82 | THRB (0.46) | THRBALDH1A1TSHRCA9CA14 | |
| SCHEMBL93999 | 0.82 | THRB (1.00) | THRBCYP3A4ALDH1A1CA1CA2 | |
| SCHEMBL22134259 | 0.80 | THRB (0.75) | THRBCYP3A4ALDH1A1CA1CA2 | |
| Hydrochloric Acid SCHEMBL10336483 | 0.79 | THRB (0.94) | THRBCYP3A4ALDH1A1CA1CA2 | |
| Hydrochloric Acid SCHEMBL2876394 | 0.79 | THRB (0.43) | THRBALDH1A1TSHRHSD17B10RECQL | |
| SCHEMBL9453347 | 0.79 | THRB (0.94) | THRBCYP3A4ALDH1A1CA1CA2 | |
| SCHEMBL5271617 | 0.79 | THRB (0.94) | THRBCYP3A4ALDH1A1CA1CA2 | |
| Hydrochloric Acid SCHEMBL7755405 | 0.79 | THRB (0.94) | THRBCYP3A4ALDH1A1CA1CA2 | |
| SCHEMBL22133464 | 0.77 | THRB (0.42) | THRBCYP3A4ALDH1A1TSHRCASP1 | |
| Hydrochloric Acid SCHEMBL10336482 | 0.75 | THRB (0.84) | THRBCYP3A4ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139795-A1 | Preparation of halogenated 4-aminophenols | LANXESS DEUTSCHLAND GMBH (DE) | 2008-06-12 | — | — | US | claimed |
| US-20050143425-A1 | Preparation of halogenated 4-aminophenols | LANXESS DEUTSCHLAND GMBH (DE) | 2005-06-30 | — | — | US | claimed |
| CN-1616412-A | Process for the preparation of halogen containing 4-amino phenols | BAYER CHEMICALS AG (DE) | 2005-05-18 | — | — | CN | claimed |
| EP-1514865-A1 | Process for the preparation of halogen containing 4-amino phenols | Bayer Chemicals AG (DE) | 2005-03-16 | — | — | EP | claimed |
| US-20250340542-A1 | THYROID HORMONE RECEPTOR AGONISTS | INVENTISBIO CO LTD (CN) | 2025-11-06 | — | — | US | disclosed |
| US-12391677-B2 | Thyroid hormone receptor agonists | InventisBio Co., Ltd. (CN) | 2025-08-19 | — | — | US | disclosed |
| CN-119552152-A | Thyroid hormone receptor agonists | 益方生物科技(上海)股份有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-112739692-B | Thyroid hormone receptor agonists | 益方生物科技(上海)股份有限公司 | 2024-11-22 | — | — | CN | disclosed |
| US-12071425-B2 | Phenoxy-pyridyl-pyrimidine compounds and methods of use | GENENTECH, INC. (US) | 2024-08-27 | — | — | US | disclosed |
| EP-3849664-B1 | PHENOXY-PYRIDYL-PYRIMIDINE COMPOUNDS AND METHODS OF USE | GENENTECH INC (US) | 2024-06-12 | — | — | EP | disclosed |
| US-20230057166-A1 | PHENOXY-PYRIDYL-PYRIMIDINE COMPOUNDS AND METHODS OF USE | GENENTECH INC (US) | 2023-02-23 | — | — | US | disclosed |
| US-20230057166-A1 | PHENOXY-PYRIDYL-PYRIMIDINE COMPOUNDS AND METHODS OF USE | GENENTECH INC (US) | 2023-02-23 | — | — | US | disclosed |
| EP-1608639-A2 | NOVEL BICYCLIC UREA DERIVATIVES USEFUL IN THE TREATMENT OF CANCER AND OTHER DISORDERS | Bayer Pharmaceuticals Corporation (US) | 2005-12-28 | — | — | EP | disclosed |
| US-20050143425-A1 | Preparation of halogenated 4-aminophenols | LANXESS DEUTSCHLAND GMBH (DE) | 2005-06-30 | — | — | US | disclosed |
| CN-1616412-A | Process for the preparation of halogen containing 4-amino phenols | BAYER CHEMICALS AG (DE) | 2005-05-18 | — | — | CN | disclosed |
| EP-1514865-A1 | Process for the preparation of halogen containing 4-amino phenols | Bayer Chemicals AG (DE) | 2005-03-16 | — | — | EP | disclosed |
| EP-1514865-A1 | Process for the preparation of halogen containing 4-amino phenols | Bayer Chemicals AG (DE) | 2005-03-16 | — | — | EP | disclosed |
| US-20050038031-A1 | Novel bicyclic urea derivatives useful in the treatment of cancer and other disorders | BAYER HEALTHCARE LLC | 2005-02-17 | — | — | US | disclosed |
| WO-2004078748-A2 | NOVEL BICYCLIC UREA DERIVATIVES USEFUL IN THE TREATMENT OF CANCER AND OTHER DISORDERS | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-09-16 | — | — | WO | disclosed |
| US-5068436-A | Hydrogenation of halonitrobenzenes without dehalogenation | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038031-A1 | Novel bicyclic urea derivatives useful in the treatment of cancer and other disorders | CCNC, UACA, SLC14A1 | THRB 4347/4885CYP3A4 3161/4885ALDH1A1 1861/4885 |
| US-12391677-B2 | Thyroid hormone receptor agonists | TSHR, THRA, TRHR | THRB 4/4885CYP3A4 787/4885ALDH1A1 1881/4885 |
| US-20230057166-A1 | PHENOXY-PYRIDYL-PYRIMIDINE COMPOUNDS AND METHODS OF USE | XBP1, ERN1, ESR2 | THRB 368/4885CYP3A4 1034/4885ALDH1A1 2362/4885 |
| US-20250340542-A1 | THYROID HORMONE RECEPTOR AGONISTS | TSHR, THRA, TRHR | THRB 4/4885CYP3A4 805/4885ALDH1A1 1827/4885 |
| US-20080139795-A1 | Preparation of halogenated 4-aminophenols | CYP4X1, CYP4B1, PAH | THRB 1714/4885CYP3A4 6/4885ALDH1A1 569/4885 |
| US-12071425-B2 | Phenoxy-pyridyl-pyrimidine compounds and methods of use | XBP1, ERN1, ESR2 | THRB 368/4885CYP3A4 1034/4885ALDH1A1 2362/4885 |
| US-20050143425-A1 | Preparation of halogenated 4-aminophenols | CYP4X1, HPD, CYP4F8 | THRB 1495/4885CYP3A4 11/4885ALDH1A1 956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.