Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7218028 | 0.84 | ALDH1A1 (0.76) | ALDH1A1HPGDTSHRSMN1; SMN2MAPK1 | |
| SCHEMBL4841450 | 0.83 | LMNA (0.58) | ALDH1A1HPGDTSHRSMN1; SMN2MAPK1 | |
| SCHEMBL31316798 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HPGDTSHRSMN1; SMN2MAPK1 | |
| SCHEMBL3943926 | 0.78 | ALDH1A1 (0.52) | ALDH1A1HPGDTSHRSMN1; SMN2MAPK1 | |
| SCHEMBL11585022 | 0.78 | ALDH1A1 (0.59) | ALDH1A1HPGDTSHRMAPK1NPC1 | |
| SCHEMBL828475 | 0.77 | AR (0.53) | ALDH1A1HPGDTSHRSMN1; SMN2MAPK1 | |
| SCHEMBL9793348 | 0.77 | ADRB1 (0.64) | ALDH1A1HPGDTSHRKDM4EHTR1A | |
| SCHEMBL7989284 | 0.77 | SMN1; SMN2 (0.52) | ALDH1A1HPGDTSHRSMN1; SMN2MAPK1 | |
| SCHEMBL3948176 | 0.77 | ALDH1A1 (0.51) | ALDH1A1HPGDTSHRSMN1; SMN2MAPK1 | |
| SCHEMBL12465718 | 0.76 | L3MBTL1 (0.56) | HPGDTSHRSMN1; SMN2GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465811-B2 | Indoline compounds | LABORATOIRES FOURNIER S.A. (FR) | 2008-12-16 | — | — | US | disclosed |
| US-20080119465-A1 | Novel Indoline Compounds | LABORATORIES FOURNIER S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119465-A1 | Novel Indoline Compounds | GPR119, INSR, IRS1 | ALDH1A1 1819/4885HPGD 3316/4885TSHR 681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.