Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.64 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.64 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.64 |
| ▸ | TSHR | P16473 | 5/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.64 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.64 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.64 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.64 |
| ▸ | DRD3 | P35462 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Metanephrine SCHEMBL29569242 | 0.84 | SLC22A3 (0.73) | KDM4EADRB2HIF1ATDP1MAPT | |
| SCHEMBL11647079 | 0.84 | KDM4E (0.68) | KDM4EADRB2HIF1ATDP1MAPT | |
| Metanephrine SCHEMBL136702 | 0.84 | SLC22A3 (0.73) | KDM4EADRB2HIF1ATDP1MAPT | |
| Metanephrine SCHEMBL30512034 | 0.84 | SLC22A3 (0.73) | KDM4EADRB2HIF1ATDP1MAPT | |
| Metanephrine SCHEMBL2471378 | 0.83 | SLC22A3 (0.71) | KDM4EADRB2HIF1ATDP1MAPT | |
| SCHEMBL2691392 | 0.83 | KDM4E (0.66) | KDM4EADRB2HIF1ATDP1MAPT | |
| SCHEMBL9435060 | 0.82 | KDM4E (0.64) | KDM4EADRB2HIF1ATDP1MAPT | |
| SCHEMBL4849450 | 0.81 | NFKB1 (0.71) | KDM4EADRB2HIF1ATDP1MAPT | |
| SCHEMBL344950 | 0.81 | KDM4E (0.62) | KDM4EADRB2HIF1ATDP1MAPT | |
| SCHEMBL23318541 | 0.80 | ADRB2 (0.57) | KDM4EADRB2HIF1ATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114042121-A | Sustained-release pellet preparation for treating chronic congestive heart failure and preparation method thereof | 杜恒 | 2022-02-15 | — | — | CN | disclosed |
| CN-110755590-B | Heart protecting capsule and preparation method thereof | 江苏黄河药业股份有限公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-108452079-B | Methods and compositions for delaying senescence, inhibiting tumor cell growth, and improving microcirculation | 江西天元药业有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-106061491-B | Bacterial influence on appetite regulation by mimicking the CLPB protein of Alpha-MSH | 国家医疗保健研究所 | 2021-01-08 | — | — | CN | disclosed |
| CN-111419965-A | Traditional Chinese medicine formula for treating varicosity, rheumatism and pain and preparation method thereof | 陕西仁浩医疗器械有限公司 | 2020-07-17 | — | — | CN | disclosed |
| CN-110755590-A | Heart protecting capsule and preparation method thereof | 江苏黄河药业股份有限公司 | 2020-02-07 | — | — | CN | disclosed |
| US-10010573-B2 | Engineered rice having alcoholism relief and liver protection function, and preparation method thereof | CHINA NATIONAL RESEARCH INSTITUTE OF FOOD AND FERMENTATION INDUSTRIES CO., LTD. (CN) | 2018-07-03 | — | — | US | disclosed |
| US-20150118336-A1 | ENGINEERED RICE HAVING ALCOHOLISM RELIEF AND LIVER PROTECTION FUNCTION, AND PREPARATION METHOD THEREOF | CHINA NATIONAL RESEARCH INSTITUTE OF FOOD AND FERMENTATION INDUSTRIES CO., LTD. (CN) | 2015-04-30 | — | — | US | disclosed |
| US-7384657-B2 | Composition of natural herb extract for treating cardiovascular disease and its method of preparation thereof | YOUNG JEFFREY | 2008-06-10 | — | — | US | disclosed |
| US-20060083798-A1 | Composition of natural herb extract for treating cardiovascular disease and its method of preparation thereof | YOUNG JEFFREY | 2006-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060083798-A1 | Composition of natural herb extract for treating cardiovascular disease and its method of preparation thereof | MATR3, MMP7, TNNI3 | KDM4E 2383/4885ADRB2 2636/4885HIF1A 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.