Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PYGB | P11216 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | PYGL | P06737 | 2/20 | 0.32 |
| ▸ | PYGM | P11217 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28973925 | 0.89 | PYGB (0.33) | PYGBPYGLPYGM | |
| SCHEMBL157466 | 0.89 | KDM4E (0.34) | KDM4EGLAGAAPYGBPOLB | |
| SCHEMBL8804692 | 0.83 | PYGB (0.32) | PYGBPYGLPYGM | |
| SCHEMBL5954319 | 0.82 | TK1 (0.37) | PYGBPOLBPYGLPYGM | |
| SCHEMBL27900812 | 0.81 | PYGM (0.33) | PYGBPYGLPYGM | |
| SCHEMBL27900813 | 0.81 | PYGB (0.34) | PYGBPYGLPYGM | |
| SCHEMBL28192010 | 0.81 | PYGM (0.33) | KDM4EGLAGAAPYGBPYGM | |
| SCHEMBL513129 | 0.79 | PYGL (0.31) | PYGBPYGLPYGM | |
| SCHEMBL15122726 | 0.78 | PYGM (0.35) | PYGBPYGM | |
| SCHEMBL14842249 | 0.77 | PYGM (0.33) | KDM4EGLAGAAPYGBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12077754-B2 | Synthetic transfer RNA with extended anticodon loop | ARCTURUS THERAPEUTICS, INC. (US) | 2024-09-03 | — | — | US | disclosed |
| US-20230183685-A1 | SYNTHETIC TRANSFER RNA WITH EXTENDED ANTICODON LOOP | ARCTURUS THERAPEUTICS, INC. | 2023-06-15 | — | — | US | disclosed |
| US-11434485-B2 | Synthetic transfer RNA with extended anticodon loop | ARCTURUS THERAPEUTICS, INC. (US) | 2022-09-06 | — | — | US | disclosed |
| US-20220162612-A1 | SYNTHETIC TRANSFER RNA WITH EXTENDED ANTICODON LOOP | ARCTURUS THERAPEUTICS, INC. | 2022-05-26 | — | — | US | disclosed |
| EP-3953469-A1 | SYNTHETIC TRANSFER RNA WITH EXTENDED ANTICODON LOOP | Arcturus Therapeutics, Inc. (US) | 2022-02-16 | — | — | EP | disclosed |
| EP-3765609-A1 | SYNTHETIC TRANSFER RNA WITH EXTENDED ANTICODON LOOP | Universität Hamburg (DE) | 2021-01-20 | — | — | EP | disclosed |
| US-20200407714-A1 | SYNTHETIC TRANSFER RNA WITH EXTENDED ANTICODON LOOP | ARCTURUS THERAPEUTICS, INC. | 2020-12-31 | — | — | US | disclosed |
| WO-2020208169-A1 | SYNTHETIC TRANSFER RNA WITH EXTENDED ANTICODON LOOP | UNIVERSITÄT HAMBURG (DE) | 2020-10-15 | — | — | WO | disclosed |
| WO-2019175316-A1 | SYNTHETIC TRANSFER RNA WITH EXTENDED ANTICODON LOOP | UNIVERSITÄT HAMBURG (DE) | 2019-09-19 | — | — | WO | disclosed |
| CN-106421773-A | VIRION-LIKE DELIVERY PARTICLES FOR SELF-REPLICATING RNA MOLECULES | 诺华股份有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-104105504-A | Recombinant polycistronic nucleic acid molecules | NOVARTIS AG | 2014-10-15 | — | — | CN | disclosed |
| CN-102282255-B | Compositions and methods for the assembly of polynucleotides | AMYRIS INC | 2014-05-07 | — | — | CN | disclosed |
| CN-103269713-A | Antigen delivery platforms | NOVARTIS AG | 2013-08-28 | — | — | CN | disclosed |
| CN-101027390-B | Lrp4/Corin dopaminergic neuron progenitor cell marker | EISAI CO LTD | 2012-12-12 | — | — | CN | disclosed |
| CN-102481364-A | Methods of treating HER2 positive cancers with HER2 receptor antagonists in combination with multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin | ENZON PHARMACEUTICALS INC | 2012-05-30 | — | — | CN | disclosed |
| CN-102282255-A | Compositions and methods for the assembly of polynucleotides | — | 2011-12-14 | — | — | CN | disclosed |
| CN-101400993-A | Microfluidic systems including porous polymer electrodes | APPLERA CORP (US) | 2009-04-01 | — | — | CN | disclosed |
| US-7452705-B2 | N4 virion single-stranded DNA dependent RNA polymerase | THE UNIVERSITY OF CHICAGO (US) | 2008-11-18 | — | — | US | disclosed |
| CN-101027390-A | Lrp4/Corin dopamine-producing neuron precursor cell marker | EISAI CO LTD (JP) | 2007-08-29 | — | — | CN | disclosed |
| CN-1745488-A | Chemical switching of nucleic acid circuit elements | UNIV SASKATCHEWAN (CA) | 2006-03-08 | — | — | CN | disclosed |