Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 2/20 | 0.35 |
| ▸ | PYGB | P11216 | 1/20 | 0.35 |
| ▸ | PYGM | P11217 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12658380 | 0.88 | TK1 (0.43) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL1825757 | 0.88 | TK1 (0.43) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL27900813 | 0.87 | PYGB (0.34) | PYGLPYGBPYGM | |
| SCHEMBL27900812 | 0.85 | PYGM (0.33) | PYGLPYGBPYGM | |
| SCHEMBL28973925 | 0.84 | PYGB (0.33) | PYGLPYGBPYGM | |
| SCHEMBL25191053 | 0.82 | TK1 (0.37) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL8804692 | 0.82 | PYGB (0.32) | PYGLPYGBPYGM | |
| SCHEMBL4849542 | 0.82 | KDM4E (0.33) | POLBPYGLPYGBPYGM | |
| SCHEMBL16669918 | 0.81 | TK1 (0.34) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL513129 | 0.80 | PYGL (0.31) | PYGLPYGBPYGM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611249-A4 | OLIGORIBONUCLEOTIDES AND RIBONUCLEASES FOR CLEAVING RNA | ISIS PHARMACEUTICALS INC (US) | 2006-06-28 | — | — | EP | disclosed |
| EP-1611249-A1 | OLIGORIBONUCLEOTIDES AND RIBONUCLEASES FOR CLEAVING RNA | ISIS PHARMACEUTICALS, INC. (US) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004097049-A1 | OLIGORIBONUCLEOTIDES AND RIBONUCLEASES FOR CLEAVING RNA | ISIS PHARMACEUTICALS, INC. (US) | 2004-11-11 | — | — | WO | disclosed |