SCHEMBL513129

SCHEMBL513129

C[C@@]1(n2cc(NCC(=O)O)c(=O)[nH]c2=S)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PYGL P06737 2/20 0.31
PYGB P11216 1/20 0.31
PYGM P11217 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL547489 0.90 TYMP (0.33) PYGM
SCHEMBL28284460 0.88
SCHEMBL27900812 0.86 PYGM (0.33) PYGLPYGBPYGM
SCHEMBL8804692 0.83 PYGB (0.32) PYGLPYGBPYGM
SCHEMBL5954319 0.80 TK1 (0.37) PYGLPYGBPYGM
SCHEMBL27900813 0.79 PYGB (0.34) PYGLPYGBPYGM
SCHEMBL4849542 0.79 KDM4E (0.33) PYGLPYGBPYGM
SCHEMBL28973925 0.79 PYGB (0.33) PYGLPYGBPYGM
SCHEMBL7262195 0.75 PYGM (0.36) PYGM
SCHEMBL7872134 0.73 PYGB (0.31) PYGBPYGM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6706691-B1 BIOAVAILABILITY OF COMPOSITIONS METABOLIZED BY THE GUT P450 ISOZYMES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2004-03-16 US claimed
CN-116490622-A Methods and compositions for predicting and/or monitoring diabetes and treatment thereof 爱荷华大学研究基金会 2023-07-25 CN disclosed
CN-116348616-A Methods and compositions for predicting and/or monitoring cardiovascular disease and treatment thereof 心脏诊断公司 2023-06-27 CN disclosed
CN-109715824-A Enzymatic nucleic acid synthesis 哈佛学院董事及会员团体 2019-05-03 CN disclosed
CN-109481455-A The organic composite for treating KRAS related disease 箭头研究公司 2019-03-19 CN disclosed
US-20190024167-A1 PRIMERS AND METHODS FOR THE DETECTION AND DISCRIMINATION OF NUCLEIC ACIDS LIFE TECHNOLOGIES CORP (US) 2019-01-24 US disclosed
US-10041117-B2 Primers and methods for the detection and discrimination of nucleic acids Life Technologies Corporation (US) 2018-08-07 US disclosed
CN-108290940-A TCR and uses thereof 圣拉斐尔医院有限公司 2018-07-17 CN disclosed
CN-107708710-A Smart CAR devices, DE CAR polypeptides, Side CAR and its use 嵌合体生物工程公司 2018-02-16 CN disclosed
CN-107449921-A For differentiating the probing analysis based on cell of drug-induced toxicity mark 博格有限责任公司 2017-12-08 CN disclosed
EP-1190097-A2 IMPROVED PRIMERS AND METHODS FOR THE DETECTION AND DISCRIMINATION OF NUCLEIC ACIDS INVITROGEN CORPORATION (US) 2002-03-27 EP disclosed
EP-1185692-A1 MONOLAYER AND ELECTRODE FOR DETECTING A LABEL-BEARING TARGET AND METHOD OF USE THEREOF The University of North Carolina at Chapel Hill (US) 2002-03-13 EP disclosed
EP-1161560-A1 ELECTROPOLYMERIZABLE FILM, AND METHOD OF MAKING AND USE THEREOF The University of North Carolina at Chapel Hill (US) 2001-12-12 EP disclosed
US-6180346-B1 ELECTROCHEMICAL DETECTION OF NUCLEIC ACIDS THE UNIVERSTIY OF NORTH CAROLINA AT CHAPEL HILL 2001-01-30 US disclosed
WO-2000079009-A2 IMPROVED PRIMERS AND METHODS FOR THE DETECTION AND DISCRIMINATION OF NUCLEIC ACIDS INVITROGEN CORPORATION (US) 2000-12-28 WO disclosed
WO-2000065099-A1 MONOLAYER AND ELECTRODE FOR DETECTING A LABEL-BEARING TARGET AND METHOD OF USE THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2000-11-02 WO disclosed
US-6127127-A Monolayer and electrode for detecting a label-bearing target and method of use thereof THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2000-10-03 US disclosed
WO-2000055366-A1 ELECTROPOLYMERIZABLE FILM, AND METHOD OF MAKING AND USE THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2000-09-21 WO disclosed
US-5968745-A ELECTRODE OF SUBSTRATE HAVING ELECTROCONDUCTIVE WORKING SURFACE AND A NONCONDUCTIVE OUTER POLYMER LAYER WHERE PROBES CAN BE ATTACHED HAVING MICROFLUIDIC REACTION OPENINGS FOR TRANSITION METAL COMPLEX TO TRANSFER ELECTRONS TO SURFACE THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1999-10-19 US disclosed
CN-1192249-A Electrochemical detection of nucleic acid hybridization UNIV NORTH CAROLINA (US) 1998-09-02 CN disclosed