Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
| ▸ | GABRP | O00591 | 2/20 | 0.30 |
| ▸ | GABRD | O14764 | 2/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7878693 | 0.87 | — | — | |
| Acetic Acid SCHEMBL2682620 | 0.79 | MEN1 (0.33) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| Acetic Acid SCHEMBL1982442 | 0.79 | MEN1 (0.33) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| Acetic Acid SCHEMBL27811256 | 0.79 | TSHR (0.39) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| Acetic Acid SCHEMBL25280990 | 0.78 | MEN1 (0.35) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL10645290 | 0.75 | — | — | |
| Acetic Acid SCHEMBL28664506 | 0.73 | FFAR3 (0.47) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| Acetic Acid SCHEMBL699536 | 0.71 | FFAR3 (0.44) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| Acetic Acid SCHEMBL2523008 | 0.71 | FFAR3 (0.44) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| Acetic Acid SCHEMBL241364 | 0.71 | FFAR3 (0.44) | ALDH1A1MEN1CYP1A2THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060301-B2 | In situ mono-or diester dicarboxylate compositions | ECOLAB INC. (US) | 2006-06-13 | — | — | US | claimed |
| US-20030021853-A1 | In situ mono-or diester dicarboxylate compositions | ECOLAB USA INC. | 2003-01-30 | — | — | US | claimed |
| WO-2003005818-A1 | IN SITUMONO-OR DIESTER DICARBOXYLATE COMPOSITIONS | ECOLAB INC. (US) | 2003-01-23 | — | — | WO | claimed |
| US-11241658-B2 | Compositions and methods for the reduction of biofilm and spores from membranes | ECOLAB USA INC. (US) | 2022-02-08 | — | — | US | disclosed |
| EP-3752278-A1 | COMPOSITIONS AND METHODS FOR THE REDUCTION OF BIOFILM AND SPORES FROM MEMBRANES | Ecolab USA Inc. (US) | 2020-12-23 | — | — | EP | disclosed |
| US-20190275468-A1 | COMPOSITIONS AND METHODS FOR THE REDUCTION OF BIOFILM AND SPORES FROM MEMBRANES | ECOLAB USA INC. | 2019-09-12 | — | — | US | disclosed |
| WO-2019160948-A1 | COMPOSITIONS AND METHODS FOR THE REDUCTION OF BIOFILM AND SPORES FROM MEMBRANES | ECOLAB USA INC. (US) | 2019-08-22 | — | — | WO | disclosed |
| US-9795132-B2 | Couplers for medium-chain fatty acids and disinfecting compositions | ECOLAB USA INC. (US) | 2017-10-24 | — | — | US | disclosed |
| US-20170258079-A1 | COUPLERS FOR MEDIUM-CHAIN FATTY ACIDS AND DISINFECTING COMPOSITIONS | ECOLAB USA INC. | 2017-09-14 | — | — | US | disclosed |
| US-9686981-B2 | Couplers for medium-chain fatty acids and disinfecting compositions | ECOLAB USA INC. (US) | 2017-06-27 | — | — | US | disclosed |
| US-20150173352-A1 | COUPLERS FOR MEDIUM-CHAIN FATTY ACIDS AND DISINFECTING COMPOSITIONS | ECOLAB USA INC. | 2015-06-25 | — | — | US | disclosed |
| US-6927237-B2 | Two solvent antimicrobial compositions and methods employing them | ECOLAB INC. (US) | 2005-08-09 | — | — | US | disclosed |
| US-20050096245-A1 | Two solvent antimicrobial compositions and methods employing them | ECOLAB INC. (US) | 2005-05-05 | — | — | US | disclosed |
| WO-2005015996-A1 | ANTIMICROBIAL COMPOSITIONS INCLUDING CARBOXYLIC ACIDS AND ALKOXYLATED AMINES | ECOLAB INC. (US) | 2005-02-24 | — | — | WO | disclosed |
| US-20050032668-A1 | Antimicrobial compositions including carboxylic acids and alkoxylated amines | ECOLAB USA INC. | 2005-02-10 | — | — | US | disclosed |
| EP-1478232-A1 | DIESTER DICARBOXYLATE ANTIMICROBIAL COMPOSITIONS AND METHODS EMPLOYING THEM | ECOLAB INC. (US) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003073849-A1 | DIESTER DICARBOXYLATE ANTIMICROBIAL COMPOSITIONS AND METHODS EMPLOYING THEM | ECOLAB INC. (US) | 2003-09-12 | — | — | WO | disclosed |
| US-20030021853-A1 | In situ mono-or diester dicarboxylate compositions | ECOLAB USA INC. | 2003-01-30 | — | — | US | disclosed |
| WO-2003005818-A1 | IN SITUMONO-OR DIESTER DICARBOXYLATE COMPOSITIONS | ECOLAB INC. (US) | 2003-01-23 | — | — | WO | disclosed |
| US-20020168422-A1 | Two solvent antimicrobial compositions and methods employing them | ECOLAB USA INC. | 2002-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150173352-A1 | COUPLERS FOR MEDIUM-CHAIN FATTY ACIDS AND DISINFECTING COMPOSITIONS | GFER, ACADM, HAO2 | ALDH1A1 707/4885MEN1 1253/4885CYP1A2 934/4885 |
| US-20030021853-A1 | In situ mono-or diester dicarboxylate compositions | DDC, HCAR3, ACMSD | ALDH1A1 590/4885MEN1 456/4885CYP1A2 509/4885 |
| US-20020168422-A1 | Two solvent antimicrobial compositions and methods employing them | TAS2R50, HDHD5, CEL | ALDH1A1 2741/4885MEN1 3490/4885CYP1A2 630/4885 |
| US-20170258079-A1 | COUPLERS FOR MEDIUM-CHAIN FATTY ACIDS AND DISINFECTING COMPOSITIONS | GFER, ACADM, HAO2 | ALDH1A1 707/4885MEN1 1253/4885CYP1A2 934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.