Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4859696 | 0.86 | KDM4E (0.39) | KDM4ELMNACYP2C19CTSKMAPT | |
| SCHEMBL2691041 | 0.72 | — | — | |
| SCHEMBL2706623 | 0.72 | SMN1; SMN2 (0.38) | KDM4ELMNACYP2C19MAPT | |
| SCHEMBL14016355 | 0.72 | SMN1; SMN2 (0.38) | KDM4ELMNACYP2C19MAPT | |
| SCHEMBL15118760 | 0.69 | LMNA (0.35) | KDM4ELMNACYP2C19 | |
| SCHEMBL578932 | 0.69 | GAA (0.35) | CYP2C19CRBN | |
| SCHEMBL15496664 | 0.69 | — | — | |
| SCHEMBL5573151 | 0.67 | KDM4E (0.32) | KDM4ELMNACYP2C19CRBN | |
| Iodide SCHEMBL6292630 | 0.67 | GAA (0.34) | CYP2C19 | |
| SCHEMBL15658264 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9643948-B2 | 2-oxo-1,3-dioxolane-4-acyl halides, their preparation and use | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2017-05-09 | — | — | US | disclosed |
| US-9617238-B2 | 2-oxo-1,3-dioxolane-4-carboxamide building blocks, their preparation and use | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-20160145232-A1 | 2-OXO-1,3-DIOXOLANE-4-ACYL HALIDES, THEIR PREPARATION AND USE | SIKA TECHNOLOGY AG (CH) | 2016-05-26 | — | — | US | disclosed |
| US-9309218-B2 | 2-Oxo-1,3-dioxolane-4-carboxamides, their preparation and use | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2016-04-12 | — | — | US | disclosed |
| US-20150353521-A1 | 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDE BUILDING BLOCKS, THEIR PREPARATION AND USE | SIKA TECHNOLOGY AG (CH) | 2015-12-10 | — | — | US | disclosed |
| US-20150051365-A1 | 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE | SIKA TECHNOLOGY AG (CH) | 2015-02-19 | — | — | US | disclosed |
| US-8940855-B2 | Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-01-27 | — | — | US | disclosed |
| US-8779166-B2 | Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-07-15 | — | — | US | disclosed |
| US-20130217853-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-08-22 | — | — | US | disclosed |
| US-8455612-B2 | Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-06-04 | — | — | US | disclosed |
| US-20120178925-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-07-12 | — | — | US | disclosed |
| US-20120172559-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-07-05 | — | — | US | disclosed |
| US-20120172603-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-07-05 | — | — | US | disclosed |
| US-20120172602-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-07-05 | — | — | US | disclosed |
| US-8207351-B2 | Cyclic carbonyl compounds with pendant carbonate groups, preparations thereof, and polymers therefrom | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-06-26 | — | — | US | disclosed |
| US-8143369-B2 | Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-03-27 | — | — | US | disclosed |
| US-20110269917-A1 | CYCLIC CARBONYL COMPOUNDS WITH PENDANT CARBONATE GROUPS, PREPARATIONS THEREOF, AND POLYMERS THEREFROM | CENTRAL GLASS CO., LTD. (JP) | 2011-11-03 | — | — | US | disclosed |
| US-8044194-B2 | Cyclic carbonyl monomers functionalized with carbohydrates, polymers derived therefrom, and methods of preparation thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2011-10-25 | — | — | US | disclosed |
| US-20100317838-A1 | CYCLIC CARBONYL MONOMERS FUNCTIONALIZED WITH CARBOHYDRATES, POLYMERS DERIVED THEREFROM, AND METHODS OF PREPARATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-12-16 | — | — | US | disclosed |
| US-20100305281-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172603-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | PFAS, PAM, PCNA | KDM4E 3560/4885LMNA 1875/4885CYP2C19 3264/4885 |
| US-20120178925-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | PFAS, PAM, PCNA | KDM4E 3560/4885LMNA 1875/4885CYP2C19 3264/4885 |
| US-20100317838-A1 | CYCLIC CARBONYL MONOMERS FUNCTIONALIZED WITH CARBOHYDRATES, POLYMERS DERIVED THEREFROM, AND METHODS OF PREPARATION THEREOF | FUT6, FUT5, WASF2 | KDM4E 3342/4885LMNA 1176/4885CYP2C19 3302/4885 |
| US-20150353521-A1 | 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDE BUILDING BLOCKS, THEIR PREPARATION AND USE | PYCR1, CBR1, NOX4 | KDM4E 1465/4885LMNA 435/4885CYP2C19 599/4885 |
| US-20100305281-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | PFAS, PAM, PCNA | KDM4E 3560/4885LMNA 1875/4885CYP2C19 3264/4885 |
| US-20110269917-A1 | CYCLIC CARBONYL COMPOUNDS WITH PENDANT CARBONATE GROUPS, PREPARATIONS THEREOF, AND POLYMERS THEREFROM | NOTUM, PFAS, PCNA | KDM4E 4160/4885LMNA 1464/4885CYP2C19 3159/4885 |
| US-20160145232-A1 | 2-OXO-1,3-DIOXOLANE-4-ACYL HALIDES, THEIR PREPARATION AND USE | AOX1, AOC2, AOC1 | KDM4E 1953/4885LMNA 1204/4885CYP2C19 1086/4885 |
| US-20120172602-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | PFAS, PAM, PCNA | KDM4E 3560/4885LMNA 1875/4885CYP2C19 3264/4885 |
| US-20150051365-A1 | 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE | HAO2, OXGR1, AOX1 | KDM4E 1037/4885LMNA 1170/4885CYP2C19 448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.