Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787825 | 0.86 | MAPT (0.40) | LMNAMAPTGAACA12CA1 | |
| SCHEMBL4786621 | 0.83 | SMN1; SMN2 (0.38) | LMNAMAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL4788883 | 0.72 | TSHR (0.39) | LMNAMAPTGAACA12CA1 | |
| SCHEMBL4752969 | 0.70 | PKM (0.46) | MAPTALDH1A1NPSR1PKM | |
| SCHEMBL4787216 | 0.68 | AKT1 (0.38) | LMNAMAPTCA12CA1CA2 | |
| SCHEMBL4750485 | 0.65 | HTR2A (0.51) | LMNAALDH1A1NPSR1PKM | |
| SCHEMBL4812505 | 0.64 | LMNA (0.41) | LMNASMN1; SMN2ALDH1A1NPSR1MAPK1 | |
| SCHEMBL4750480 | 0.64 | ALDH1A1 (0.39) | LMNAMAPTALDH1A1KDM4EPOLB | |
| SCHEMBL4788339 | 0.64 | KCNH2 (0.50) | — | |
| SCHEMBL6714846 | 0.63 | ALDH1A1 (0.75) | LMNAMAPTCA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |