Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | BUB1 | O43683 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4869078 | 1.00 | CTSL (0.47) | CTSLCTSBCTSKLMNACYP3A4 | |
| SCHEMBL7279180 | 0.91 | CYP2C19 (0.52) | CTSLCTSBCTSKLMNACYP3A4 | |
| SCHEMBL421810 | 0.90 | CTSL (0.49) | CTSLCTSBCTSKLMNABUB1 | |
| SCHEMBL337537 | 0.86 | BUB1 (0.51) | CTSLCTSBCTSKLMNABUB1 | |
| SCHEMBL15803710 | 0.84 | CYP2C19 (0.43) | CTSLCTSBCTSKLMNACYP3A4 | |
| SCHEMBL19261314 | 0.83 | BUB1 (0.49) | CTSLCTSBCTSKLMNABUB1 | |
| SCHEMBL1928095 | 0.79 | TSHR (0.58) | CTSLCTSBCTSKLMNATSHR | |
| SCHEMBL17019782 | 0.79 | TSHR (0.58) | CTSLCTSBCTSKLMNATSHR | |
| SCHEMBL1623299 | 0.78 | LMNA (0.44) | CTSLCTSBCTSKLMNACYP3A4 | |
| SCHEMBL4865573 | 0.78 | GBA1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49036-E1 | Method for synthesizing optically active carbonyl compounds | BASF SE (DE) | 2022-04-19 | — | — | US | disclosed |
| EP-3489213-B1 | COMPOSITION FOR USE IN A METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF SE (DE) | 2021-04-28 | — | — | EP | disclosed |
| EP-3489213-A1 | COMPOSITION FOR USE IN A METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF SE (DE) | 2019-05-29 | — | — | EP | disclosed |
| US-10301244-B2 | Method for synthesizing optically active carbonyl compounds | BASF SE (DE) | 2019-05-28 | — | — | US | disclosed |
| EP-3233778-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF SE (DE) | 2019-02-20 | — | — | EP | disclosed |
| US-9975837-B2 | Method for synthesizing optically active carbonyl compounds | BASF SE (DE) | 2018-05-22 | — | — | US | disclosed |
| US-9975837-B2 | Method for synthesizing optically active carbonyl compounds | BASF SE (DE) | 2018-05-22 | — | — | US | disclosed |
| US-20180057437-A1 | METHOD FOR SYNTHESIZING OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF SE (DE) | 2018-03-01 | — | — | US | disclosed |
| US-20180057437-A1 | METHOD FOR SYNTHESIZING OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF SE (DE) | 2018-03-01 | — | — | US | disclosed |
| EP-2139835-B1 | METHOD FOR SYNTHESIZING OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF SE (DE) | 2017-05-10 | — | — | EP | disclosed |
| US-20100152494-A1 | METHOD FOR SYNTHESIZING OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF SE (DE) | 2010-06-17 | — | — | US | disclosed |
| US-20100152494-A1 | METHOD FOR SYNTHESIZING OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF SE (DE) | 2010-06-17 | — | — | US | disclosed |
| US-7534921-B2 | Method for the production of optically active carbonyl | BASF AKTIENGESELLSCHAFT (DE) | 2009-05-19 | — | — | US | disclosed |
| US-7534921-B2 | Method for the production of optically active carbonyl | BASF AKTIENGESELLSCHAFT (DE) | 2009-05-19 | — | — | US | disclosed |
| WO-2008132057-A1 | METHOD FOR SYNTHESIZING OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF SE (DE) | 2008-11-06 | — | — | WO | disclosed |
| US-20080269528-A1 | Method for the Production of Optically Active Carbonyl | BASF AKTIENGESELLSCHAFT (DE) | 2008-10-30 | — | — | US | disclosed |
| US-20080269528-A1 | Method for the Production of Optically Active Carbonyl | BASF AKTIENGESELLSCHAFT (DE) | 2008-10-30 | — | — | US | disclosed |
| US-20080125310-A1 | Hydride reduction of alpha, beta-unsaturated carbonyl compounds using chiral organic catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2008-05-29 | — | — | US | disclosed |
| US-7323604-B2 | Hydride reduction of α,β-unsaturated carbonyl compounds using chiral organic catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2008-01-29 | — | — | US | disclosed |
| US-20060161024-A1 | Hydride reduction of alpha, beta-unsaturated carbonyl compounds using chiral organic catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301244-B2 | Method for synthesizing optically active carbonyl compounds | CBR3, CBR1, HRH4 | CTSL 265/4885CTSB 687/4885CTSK 864/4885 |
| US-20080269528-A1 | Method for the Production of Optically Active Carbonyl | CBR1, CBR3, HMOX1 | CTSL 2109/4885CTSB 2922/4885CTSK 2309/4885 |
| US-20060161024-A1 | Hydride reduction of alpha, beta-unsaturated carbonyl compounds using chiral organic catalysts | ECH1, CBR1, DHCR24 | CTSL 4657/4885CTSB 3816/4885CTSK 3192/4885 |
| US-20100152494-A1 | METHOD FOR SYNTHESIZING OPTICALLY ACTIVE CARBONYL COMPOUNDS | HMOX1, HMOX2, CBR1 | CTSL 2915/4885CTSB 2006/4885CTSK 1882/4885 |
| US-20180057437-A1 | METHOD FOR SYNTHESIZING OPTICALLY ACTIVE CARBONYL COMPOUNDS | CBR3, CBR1, HRH4 | CTSL 265/4885CTSB 687/4885CTSK 864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.