Sugi Predict

Sugi Predict / Compounds / SCHEMBL487054

SCHEMBL487054

SCHEMBL487054

C[N+](C)(CC[N+](C)(CC[N+](C)(CC[N+](C)(C)Cc1ccc(C(=O)c2ccccc2)cc1)Cc1ccc(C(=O)c2ccccc2)cc1)Cc1ccc(C(=O)c2ccccc2)cc1)Cc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.44
▸ SRD5A2 P31213 3/20 0.43
▸ HTT P42858 4/20 0.42
▸ SMN1; SMN2 Q16637 3/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ ATM Q13315 1/20 0.42
▸ HPGD P15428 3/20 0.41
▸ DNM1 Q05193 2/20 0.41
▸ ACHE P22303 1/20 0.41
▸ RAB9A P51151 3/20 0.41
▸ NPC1 O15118 1/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ TP53 P04637 1/20 0.41
▸ MAPK1 P28482 1/20 0.41
▸ GAA P10253 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ ELANE P08246 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL321584 1.00 ALDH1A1 (0.44) ALDH1A1SRD5A2HTTSMN1; SMN2L3MBTL1
Bromide SCHEMBL231806 0.98 DNM1 (0.43) ALDH1A1SRD5A2HTTSMN1; SMN2L3MBTL1
Bromide SCHEMBL232863 0.98 DNM1 (0.43) ALDH1A1SRD5A2HTTSMN1; SMN2L3MBTL1
SCHEMBL485968 0.94 ALDH1A1 (0.50) ALDH1A1SRD5A2HTTSMN1; SMN2L3MBTL1
Bromide SCHEMBL1205091 0.93 DNM1 (0.46) ALDH1A1SRD5A2HTTSMN1; SMN2L3MBTL1
Bromide SCHEMBL6055899 0.93 DNM1 (0.41) ALDH1A1SRD5A2HTTSMN1; SMN2L3MBTL1
Bromide SCHEMBL231675 0.92 ALDH1A1 (0.48) ALDH1A1SRD5A2HTTSMN1; SMN2L3MBTL1
SCHEMBL16731588 0.87 DNM1 (0.51) ALDH1A1SRD5A2HTTSMN1; SMN2L3MBTL1
SCHEMBL14521789 0.86 DNM1 (0.50) ALDH1A1SRD5A2HTTSMN1; SMN2L3MBTL1
SCHEMBL320399 0.86 DNM1 (0.58) ALDH1A1SRD5A2HTTSMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1503813-B1 SILANE COATING COMPOSITION SURMODICS INC (US) 2007-05-30 — — EP claimed
US-6706408-B2 Silane coating composition SURMODICS, INC. 2004-03-16 — — US claimed
US-20030215649-A1 First coating layer of a silane compound, a hydrolysis reaction product of the silane compound or a polymeric silane compound, or mixture (free of sulfide group), a second layer of a polymer and a photoactivable crosslinker SURMODICS, INC. 2003-11-20 — — US claimed
WO-2026090506-A1 MEDICAL DEVICE COATINGS AND METHODS SURMODICS, INC. (US) 2026-04-30 — — WO disclosed
US-20260108663-A1 LOW PARTICULATE LUBRICIOUS COATING WITH VINYL PYRROLIDONE AND ACIDIC POLYMER-CONTAINING LAYERS SURMODICS INC (US) 2026-04-23 — — US disclosed
US-20260108662-A1 LUBRICIOUS COATING FOR MEDICAL DEVICE SURMODICS INC (US) 2026-04-23 — — US disclosed
US-12472288-B2 Lubricious coating for medical device SURMODICS, INC. (US) 2025-11-18 — — US disclosed
EP-4646241-A1 LUBRICIOUS COATINGS FOR MEDICAL DEVICES WITH ENHANCED DURABILITY SurModics, Inc. (US) 2025-11-12 — — EP disclosed
EP-4082598-B1 LOW-FRICTION SEALING DEVICES SURMODICS INC (US) 2025-10-01 — — EP disclosed
EP-4615530-A1 POLYACRYLIC ACID CONTAINING LUBRICIOUS COATINGS FOR MEDICAL DEVICES WITH ENHANCED PROPERTIES SurModics, Inc. (US) 2025-09-17 — — EP disclosed
US-12409253-B2 Low particulate lubricious coating with vinyl pyrrolidone and acidic polymer-containing layers SURMODICS, INC. (US) 2025-09-09 — — US disclosed
US-20070054127-A1 SILANE COATING COMPOSITIONS, COATING SYSTEMS, AND METHODS Surmodics Coatings, LLC 2007-03-08 — — US disclosed
WO-2006130776-A2 HYDROPHILIC POLYMERIC COATINGS FOR MEDICAL ARTICLES SURMODICS, INC. (US) 2006-12-07 — — WO disclosed
US-20060276894-A1 Hydrophilic polymeric coatings for medical articles SURMODICS, INC. 2006-12-07 — — US disclosed
WO-2006099470-A2 COMPLIANT POLYMERIC COATINGS FOR INSERTABLE MEDICAL ARTICLES SURMODICS, INC. (US) 2006-09-21 — — WO disclosed
US-20060210816-A1 Compliant polymeric coatings for insertable medical articles BANK OF MONTREAL, AS COLLATERAL AGENT 2006-09-21 — — US disclosed
EP-1503813-A1 SILANE COATING COMPOSITION SurModics, Inc. (US) 2005-02-09 — — EP disclosed
US-6706408-B2 Silane coating composition SURMODICS, INC. 2004-03-16 — — US disclosed
WO-2003097117-A1 SILANE COATING COMPOSITION SURMODICS, INC. (US) 2003-11-27 — — WO disclosed
US-20030215649-A1 First coating layer of a silane compound, a hydrolysis reaction product of the silane compound or a polymeric silane compound, or mixture (free of sulfide group), a second layer of a polymer and a photoactivable crosslinker SURMODICS, INC. 2003-11-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108662-A1 LUBRICIOUS COATING FOR MEDICAL DEVICE MUC1, ADH1A, PTK2 ALDH1A1 45/4885SRD5A2 2043/4885HTT 3206/4885
US-20260108663-A1 LOW PARTICULATE LUBRICIOUS COATING WITH VINYL PYRROLIDONE AND ACIDIC POLYMER-CONTAINING LAYERS VCL, RAD54L, SELP ALDH1A1 751/4885SRD5A2 1863/4885HTT 2307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.