Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | GLI1 | P08151 | 2/20 | 0.40 |
| ▸ | GLI2 | P10070 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL321585 | 0.99 | ACHE (0.46) | ACHEGLI1GLI2ALDH1A1HPGD | |
| Bromide SCHEMBL231807 | 0.97 | ACHE (0.44) | ACHEGLI1GLI2ALDH1A1HPGD | |
| Bromide SCHEMBL232864 | 0.96 | ACHE (0.45) | ACHEGLI1GLI2ALDH1A1HPGD | |
| Bromide SCHEMBL6055901 | 0.91 | ACHE (0.43) | ACHEGLI1GLI2ALDH1A1HPGD | |
| SCHEMBL28202434 | 0.83 | SRD5A2 (0.45) | ACHEALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL485968 | 0.83 | ALDH1A1 (0.50) | ACHEALDH1A1HPGDNPC1RAB9A | |
| Bromide SCHEMBL231675 | 0.81 | ALDH1A1 (0.48) | ACHEALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL5051511 | 0.80 | ACHE (0.56) | ACHEHPGDNPC1RAB9ABCHE | |
| SCHEMBL16731588 | 0.80 | DNM1 (0.51) | ACHEALDH1A1HPGDNPC1RAB9A | |
| Bromide SCHEMBL4003015 | 0.80 | ACHE (0.45) | ACHEALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1503813-B1 | SILANE COATING COMPOSITION | SURMODICS INC (US) | 2007-05-30 | — | — | EP | claimed |
| US-6706408-B2 | Silane coating composition | SURMODICS, INC. | 2004-03-16 | — | — | US | claimed |
| US-20030215649-A1 | First coating layer of a silane compound, a hydrolysis reaction product of the silane compound or a polymeric silane compound, or mixture (free of sulfide group), a second layer of a polymer and a photoactivable crosslinker | SURMODICS, INC. | 2003-11-20 | — | — | US | claimed |
| WO-2026090506-A1 | MEDICAL DEVICE COATINGS AND METHODS | SURMODICS, INC. (US) | 2026-04-30 | — | — | WO | disclosed |
| US-20260108663-A1 | LOW PARTICULATE LUBRICIOUS COATING WITH VINYL PYRROLIDONE AND ACIDIC POLYMER-CONTAINING LAYERS | SURMODICS INC (US) | 2026-04-23 | — | — | US | disclosed |
| US-20260108662-A1 | LUBRICIOUS COATING FOR MEDICAL DEVICE | SURMODICS INC (US) | 2026-04-23 | — | — | US | disclosed |
| US-12472288-B2 | Lubricious coating for medical device | SURMODICS, INC. (US) | 2025-11-18 | — | — | US | disclosed |
| EP-4082598-B1 | LOW-FRICTION SEALING DEVICES | SURMODICS INC (US) | 2025-10-01 | — | — | EP | disclosed |
| US-12409253-B2 | Low particulate lubricious coating with vinyl pyrrolidone and acidic polymer-containing layers | SURMODICS, INC. (US) | 2025-09-09 | — | — | US | disclosed |
| US-20250229008-A1 | DELIVERY OF HYDROPHOBIC ACTIVE AGENT PARTICLES | BANK OF MONTREAL, AS COLLATERAL AGENT | 2025-07-17 | — | — | US | disclosed |
| US-20250144182-A1 | ACTIVE AGENT DEPOTS FORMED IN SITU FOR MAINTAINING LONG-TERM LESION PATENCY | BANK OF MONTREAL, AS COLLATERAL AGENT | 2025-05-08 | — | — | US | disclosed |
| US-20070054127-A1 | SILANE COATING COMPOSITIONS, COATING SYSTEMS, AND METHODS | Surmodics Coatings, LLC | 2007-03-08 | — | — | US | disclosed |
| WO-2006130776-A2 | HYDROPHILIC POLYMERIC COATINGS FOR MEDICAL ARTICLES | SURMODICS, INC. (US) | 2006-12-07 | — | — | WO | disclosed |
| US-20060276894-A1 | Hydrophilic polymeric coatings for medical articles | SURMODICS, INC. | 2006-12-07 | — | — | US | disclosed |
| WO-2006099470-A2 | COMPLIANT POLYMERIC COATINGS FOR INSERTABLE MEDICAL ARTICLES | SURMODICS, INC. (US) | 2006-09-21 | — | — | WO | disclosed |
| US-20060210816-A1 | Compliant polymeric coatings for insertable medical articles | BANK OF MONTREAL, AS COLLATERAL AGENT | 2006-09-21 | — | — | US | disclosed |
| EP-1503813-A1 | SILANE COATING COMPOSITION | SurModics, Inc. (US) | 2005-02-09 | — | — | EP | disclosed |
| US-6706408-B2 | Silane coating composition | SURMODICS, INC. | 2004-03-16 | — | — | US | disclosed |
| WO-2003097117-A1 | SILANE COATING COMPOSITION | SURMODICS, INC. (US) | 2003-11-27 | — | — | WO | disclosed |
| US-20030215649-A1 | First coating layer of a silane compound, a hydrolysis reaction product of the silane compound or a polymeric silane compound, or mixture (free of sulfide group), a second layer of a polymer and a photoactivable crosslinker | SURMODICS, INC. | 2003-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250144182-A1 | ACTIVE AGENT DEPOTS FORMED IN SITU FOR MAINTAINING LONG-TERM LESION PATENCY | PLAT, VEGFA, FGB | ACHE 2276/4885GLI1 1078/4885GLI2 3176/4885 |
| US-20260108662-A1 | LUBRICIOUS COATING FOR MEDICAL DEVICE | MUC1, ADH1A, PTK2 | ACHE 1657/4885GLI1 1102/4885GLI2 2630/4885 |
| US-20250229008-A1 | DELIVERY OF HYDROPHOBIC ACTIVE AGENT PARTICLES | AHR, KRT18, CD44 | ACHE 845/4885GLI1 1399/4885GLI2 2932/4885 |
| US-20260108663-A1 | LOW PARTICULATE LUBRICIOUS COATING WITH VINYL PYRROLIDONE AND ACIDIC POLYMER-CONTAINING LAYERS | VCL, RAD54L, SELP | ACHE 3530/4885GLI1 3068/4885GLI2 4537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.