Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.75 |
| ▸ | RAB9A | P51151 | 10/20 | 0.75 |
| ▸ | HPGD | P15428 | 10/20 | 0.75 |
| ▸ | NPC1 | O15118 | 8/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.75 |
| ▸ | TSHR | P16473 | 2/20 | 0.75 |
| ▸ | CASP3 | P42574 | 2/20 | 0.75 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.75 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.75 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.75 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.75 |
| ▸ | MAPT | P10636 | 2/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10715396 | 0.97 | RAB9A (0.76) | ALDH1A1RAB9AHPGDNPC1KDM4E | |
| SCHEMBL10626253 | 0.86 | ALDH1A1 (0.69) | ALDH1A1RAB9AHPGDNPC1KDM4E | |
| SCHEMBL3249622 | 0.86 | RAB9A (1.00) | ALDH1A1RAB9AHPGDNPC1KDM4E | |
| SCHEMBL10714331 | 0.86 | KDM4E (0.74) | ALDH1A1RAB9AHPGDNPC1KDM4E | |
| SCHEMBL3247178 | 0.86 | RAB9A (1.00) | ALDH1A1RAB9AHPGDNPC1KDM4E | |
| SCHEMBL10716764 | 0.82 | KDM4E (0.68) | ALDH1A1RAB9AHPGDNPC1KDM4E | |
| SCHEMBL13930933 | 0.78 | RAB9A (0.63) | ALDH1A1RAB9AHPGDNPC1KDM4E | |
| SCHEMBL13930925 | 0.78 | ALDH1A1 (0.62) | ALDH1A1RAB9AHPGDNPC1KDM4E | |
| SCHEMBL74359 | 0.78 | ALOX15 (0.96) | ALDH1A1RAB9AHPGDNPC1KDM4E | |
| SCHEMBL10716443 | 0.77 | MAPT (0.62) | ALDH1A1RAB9AHPGDNPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015193-A1 | Certain azoles exhibiting ATP-utilizing enzyme inhibitory activity, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2008-01-17 | — | — | US | claimed |
| US-10827753-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2020-11-10 | — | — | US | disclosed |
| US-20190343120-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-11-14 | — | — | US | disclosed |
| US-20190327967-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-10-31 | — | — | US | disclosed |
| US-10375958-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2019-08-13 | — | — | US | disclosed |
| US-20190021325-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-01-24 | — | — | US | disclosed |
| CN-105658638-B | compounds with insecticidal activity | 拜耳作物科学股份公司 | 2018-07-06 | — | — | CN | disclosed |
| CN-105578885-B | Imidazo thiophene (two) azoles sulfonamide as nematicide | 拜耳作物科学股份公司 | 2018-06-26 | — | — | CN | disclosed |
| US-9868719-B2 | Compounds with pesticidal activity | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-16 | — | — | US | disclosed |
| US-20170367338-A1 | COMPOSITIONS AND METHODS FOR IMPROVING AGRONOMIC CHARACTERISTICS OF PLANTS | MONSANTO TECHNOLOGY LLC (US) | 2017-12-28 | — | — | US | disclosed |
| US-7741348-B2 | Bisheterocycle tandem compounds useful as antiviral agents, the uses thereof and the compositions comprising such compounds | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2010-06-22 | — | — | US | disclosed |
| US-7741348-B2 | Bisheterocycle tandem compounds useful as antiviral agents, the uses thereof and the compositions comprising such compounds | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2010-06-22 | — | — | US | disclosed |
| WO-2009023721-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | DIVERGENCE, INC. (US) | 2009-02-19 | — | — | WO | disclosed |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | MONSANTO TECHNOLOGY LLC | 2009-02-19 | — | — | US | disclosed |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | MONSANTO TECHNOLOGY LLC | 2009-02-19 | — | — | US | disclosed |
| US-20080306121-A1 | Bisheterocycle Tandem Compounds Useful as Antiviral Agents, the Uses Thereof and the Compositions Comprising Such Compounds | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2008-12-11 | — | — | US | disclosed |
| US-20080306121-A1 | Bisheterocycle Tandem Compounds Useful as Antiviral Agents, the Uses Thereof and the Compositions Comprising Such Compounds | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2008-12-11 | — | — | US | disclosed |
| US-20080015193-A1 | Certain azoles exhibiting ATP-utilizing enzyme inhibitory activity, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2008-01-17 | — | — | US | disclosed |
| WO-2007149395-A2 | 2,5-SUBSTITUTED OXAZOLE DERIVATIVES AS PROTEIN KINASE INHIBITORS FOR THE TREATMENT OF CANCER | AMPHORA DISCOVERY CORPORATION (US) | 2007-12-27 | — | — | WO | disclosed |
| WO-1987006429-A1 | PHOTOACTIVE AZOLE PESTICIDES | FMC CORPORATION (US) | 1987-11-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10827753-B2 | Compositions and methods for controlling nematodes | NOP2, ATL3, CYCS | ALDH1A1 3430/4885RAB9A 3412/4885HPGD 1205/4885 |
| US-20190021325-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | ALDH1A1 3430/4885RAB9A 3412/4885HPGD 1205/4885 |
| US-20080306121-A1 | Bisheterocycle Tandem Compounds Useful as Antiviral Agents, the Uses Thereof and the Compositions Comprising Such Compounds | PCNA, HAVCR2, HCCS | ALDH1A1 3394/4885RAB9A 2448/4885HPGD 577/4885 |
| US-20190343120-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | ALDH1A1 3430/4885RAB9A 3412/4885HPGD 1205/4885 |
| US-20170367338-A1 | COMPOSITIONS AND METHODS FOR IMPROVING AGRONOMIC CHARACTERISTICS OF PLANTS | CYP51A1, MT-CO3, ACOX3 | ALDH1A1 1344/4885RAB9A 3594/4885HPGD 1340/4885 |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | NOP2, MT-CO3, CLPX | ALDH1A1 2842/4885RAB9A 4578/4885HPGD 1350/4885 |
| US-20080015193-A1 | Certain azoles exhibiting ATP-utilizing enzyme inhibitory activity, compositions, and uses thereof | ATP5ME, ATP5MG, ATP5MK | ALDH1A1 404/4885RAB9A 3960/4885HPGD 671/4885 |
| US-10375958-B2 | Compositions and methods for controlling nematodes | NOP2, ATL3, CYCS | ALDH1A1 3430/4885RAB9A 3412/4885HPGD 1205/4885 |
| US-20190327967-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | ALDH1A1 3430/4885RAB9A 3412/4885HPGD 1205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.