SCHEMBL4880585

SCHEMBL4880585

CCCC[C@H](CC(=O)NOCc1ccccc1)C(=O)N[C@H](C(=O)N1CCC(NS(=O)(=O)c2ccc(F)cc2)CC1)C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 9/20 0.42
MMP1 P03956 1/20 0.42
MMP9 P14780 1/20 0.42
MMP8 P22894 1/20 0.42
MMP2 P08253 14/20 0.41
HTR1A P08908 3/20 0.39
HTR7 P34969 3/20 0.39
F13A1 P00488 1/20 0.39
TGM2 P21980 1/20 0.39
TGM1 P22735 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4883757 0.87 MMP3 (0.48) MMP3MMP1MMP9MMP2
SCHEMBL4885197 0.87 MMP2 (0.44) MMP3MMP1MMP2HTR1AHTR7
SCHEMBL4885026 0.84 MMP13 (0.42) MMP3MMP1MMP2HTR1AHTR7
SCHEMBL4876342 0.74 MMP2 (0.63) MMP3MMP1MMP9MMP8MMP2
SCHEMBL4884939 0.74 MMP3 (0.52) MMP3MMP1MMP9MMP2
SCHEMBL4886950 0.73 MMP13 (0.48) HTR1AHTR7
SCHEMBL6298283 0.72 MMP3 (0.49) MMP3MMP1MMP9MMP8MMP2
SCHEMBL4885918 0.72 MMP2 (0.59) MMP3MMP1MMP9MMP8MMP2
SCHEMBL8101473 0.71 MMP2 (0.65) MMP3MMP1MMP9MMP8MMP2
SCHEMBL5494014 0.69 MMP1 (0.44) MMP3MMP1MMP9MMP8MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080234333-A1 Novel Hydroxamic Acid Derivative as Peptide Deformylase Inhibitor and Manufacturing Method Thereof KANG JAE-HOON 2008-09-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080234333-A1 Novel Hydroxamic Acid Derivative as Peptide Deformylase Inhibitor and Manufacturing Method Thereof PDF, PEPD, DHPS MMP3 362/4885MMP1 885/4885MMP9 639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.