SCHEMBL4882781

SCHEMBL4882781

BrC1(N(c2ccc3ccccc3c2)c2ccc3ccccc3c2)C=CC(c2ccccc2)C=C1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.31
MAOA P21397 2/20 0.31
MAOB P27338 2/20 0.31
CYP2A6 P11509 1/20 0.31
KDM4E B2RXH2 1/20 0.30
INSR P06213 1/20 0.30
IGF1R P08069 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2802019 0.82 KDM1A (0.31) KDM1AMAOAMAOBKDM4EINSR
SCHEMBL8209205 0.78
SCHEMBL21500411 0.76 SIGMAR1 (0.32)
SCHEMBL5148248 0.72 ALDH1A1 (0.35) MAOACYP2A6
SCHEMBL5526902 0.72 KDM1A (0.31) KDM1AMAOAMAOB
SCHEMBL8211332 0.69 CYP1A2 (0.32) MAOA
SCHEMBL2390258 0.67 HTR2C (0.32) KDM1AMAOAMAOBCYP2A6
SCHEMBL7427186 0.66 KDM1A (0.39) KDM1AMAOAMAOB
SCHEMBL6761166 0.65 RAB9A (0.31)
SCHEMBL710236 0.65 ALDH1A1 (0.33) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080124455-A1 ORGANIC LIGHT EMITTING COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME, AND METHOD OF MANUFACTURING THE ORGANIC LIGHT EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080124455-A1 ORGANIC LIGHT EMITTING COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME, AND METHOD OF MANUFACTURING THE ORGANIC LIGHT EMITTING DEVICE CYBA, CRY2, CRY1 KDM1A 2641/4885MAOA 1349/4885MAOB 1312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.