Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 10/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4888690 | 0.80 | SLC22A12 (0.57) | SLC22A12MAOAMAOBPPARA | |
| SCHEMBL12426830 | 0.79 | ALDH1A1 (0.41) | SLC22A12ALDH1A1MAPTMAOACA1 | |
| SCHEMBL3285117 | 0.79 | SMN1; SMN2 (0.41) | SLC22A12ALDH1A1MAPT | |
| SCHEMBL2818700 | 0.78 | MAPT (0.42) | ALDH1A1MAPTCA1CA2 | |
| SCHEMBL5227021 | 0.76 | PTPRZ1 (0.38) | — | |
| SCHEMBL6364141 | 0.76 | ALDH1A1 (0.43) | ALDH1A1MAPT | |
| SCHEMBL4877710 | 0.75 | LOXL2 (0.40) | MAOB | |
| SCHEMBL2823545 | 0.75 | CA1 (0.44) | ALDH1A1MAPTCA1CA2 | |
| Hydrochloric Acid SCHEMBL4927261 | 0.74 | LOXL2 (0.39) | MAOB | |
| SCHEMBL4023625 | 0.73 | KIF11 (0.43) | ALDH1A1MAPTGPR119EGLN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080261990-A1 | Novel Pyrimidine Derivatives and their Use | BAYER HEALTHCARE AG (DE) | 2008-10-23 | — | — | US | disclosed |
| US-20080261990-A1 | Novel Pyrimidine Derivatives and their Use | BAYER HEALTHCARE AG (DE) | 2008-10-23 | — | — | US | disclosed |
| US-20080255202-A1 | Phenylthioacetic Acid Derivatives and Use Thereof | BAYER HEALTHCARE AG (DE) | 2008-10-16 | — | — | US | disclosed |
| US-20080255202-A1 | Phenylthioacetic Acid Derivatives and Use Thereof | BAYER HEALTHCARE AG (DE) | 2008-10-16 | — | — | US | disclosed |
| EP-1742942-A1 | PHENYLTHIOACETIC ACID DERIVATIVES AND USE THEREOF | Bayer HealthCare AG (DE) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005097784-A1 | PHENYLTHIOACETIC ACID DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2005-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255202-A1 | Phenylthioacetic Acid Derivatives and Use Thereof | PAH, TST, MPST | SLC22A12 761/4885ALDH1A1 676/4885MAPT 1228/4885 |
| US-20080261990-A1 | Novel Pyrimidine Derivatives and their Use | TYMS, TYMP, UMPS | SLC22A12 3285/4885ALDH1A1 1944/4885MAPT 4320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.