Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13932284 | 0.77 | CES1 (0.46) | ACHELMNASMN1; SMN2ALDH1A1NOTUM | |
| SCHEMBL5845169 | 0.71 | ACHE (1.00) | ACHEALDH1A1AKR1B1KMT2ACES1 | |
| SCHEMBL16865823 | 0.71 | ACHE (0.56) | ACHELMNASMN1; SMN2ALDH1A1CHRM2 | |
| SCHEMBL216973 | 0.71 | ACHE (0.56) | ACHELMNASMN1; SMN2ALDH1A1CHRM2 | |
| SCHEMBL25385438 | 0.68 | ACHE (0.83) | ACHELMNASMN1; SMN2ALDH1A1AKR1B1 | |
| SCHEMBL9404680 | 0.68 | ACHE (0.52) | ACHELMNASMN1; SMN2ALDH1A1CHRM2 | |
| SCHEMBL31123671 | 0.66 | ACHE (0.59) | ACHELMNASMN1; SMN2ALDH1A1CHRM2 | |
| SCHEMBL31510701 | 0.66 | ACHE (0.59) | ACHELMNASMN1; SMN2ALDH1A1CHRM2 | |
| SCHEMBL86279 | 0.66 | ACHE (0.59) | ACHELMNASMN1; SMN2ALDH1A1CHRM2 | |
| SCHEMBL19334727 | 0.66 | ACHE (0.48) | ACHELMNASMN1; SMN2ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080241943-A1 | Subnanomolar Precipitator of Thiophilic Metals | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-10-02 | — | — | US | claimed |
| WO-2006055883-A2 | SUBNANOMOLAR PRECIPITATOR OF THIOPHILIC METALS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-05-26 | — | — | WO | claimed |
| US-20030082101-A1 | Accelerators for increasing the rate of formation of free radicals and reactive oxygen species | CAVALIER DISCOVERY | 2003-05-01 | — | — | US | claimed |
| EP-0707023-A1 | Method for the preparation of a heterocyclic polymer | DSM N.V. (NL) | 1996-04-17 | — | — | EP | claimed |
| US-20080241943-A1 | Subnanomolar Precipitator of Thiophilic Metals | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-10-02 | — | — | US | disclosed |
| WO-2006055883-A2 | SUBNANOMOLAR PRECIPITATOR OF THIOPHILIC METALS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-05-26 | — | — | WO | disclosed |
| US-20030082101-A1 | Accelerators for increasing the rate of formation of free radicals and reactive oxygen species | CAVALIER DISCOVERY | 2003-05-01 | — | — | US | disclosed |
| EP-0707023-A1 | Method for the preparation of a heterocyclic polymer | DSM N.V. (NL) | 1996-04-17 | — | — | EP | disclosed |
| US-5220036-A | Thiolactone dye precursors | POLAROID CORPORATION (US) | 1993-06-15 | — | — | US | disclosed |
| US-5196297-A | Recording material and process of using | POLAROID CORPORATION (US) | 1993-03-23 | — | — | US | disclosed |
| US-5028725-A | Thiolactone metal complexes | POLAROID CORPORATION (US) | 1991-07-02 | — | — | US | disclosed |
| US-4970309-A | Synthesis of thiolactones | POLAROID CORPORATION (US) | 1990-11-13 | — | — | US | disclosed |
| EP-0250558-B1 | NOVEL COMPOUNDS AND NOVEL RECORDING MATERIAL USING THE SAME | POLAROID CORPORATION (US) | 1990-05-02 | — | — | EP | disclosed |
| EP-0250558-A1 | NOVEL COMPOUNDS AND NOVEL RECORDING MATERIAL USING THE SAME. | POLAROID CORP (US) | 1988-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030082101-A1 | Accelerators for increasing the rate of formation of free radicals and reactive oxygen species | SOD1, SOD3, APEX1 | ACHE 4141/4885LMNA 3197/4885SMN1; SMN2 2626/4885 |
| US-20080241943-A1 | Subnanomolar Precipitator of Thiophilic Metals | LGALS2, LGALS4, CA2 | ACHE 4222/4885LMNA 4214/4885SMN1; SMN2 4558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.