Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 7/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.34 |
| ▸ | GABRP | O00591 | 6/20 | 0.34 |
| ▸ | GABRD | O14764 | 6/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4887298 | 0.92 | ALDH1A1 (0.39) | ALDH1A1MAPTPOLBNPC1RAB9A | |
| SCHEMBL4911401 | 0.84 | NPC1 (0.45) | ALDH1A1MAPTPOLBNPC1RAB9A | |
| SCHEMBL4914665 | 0.83 | ALDH1A1 (0.40) | ALDH1A1MAPTPOLBNPC1RAB9A | |
| SCHEMBL4640617 | 0.83 | ALDH1A1 (0.40) | ALDH1A1MAPTPOLBNPC1RAB9A | |
| SCHEMBL4907499 | 0.82 | NPC1 (0.45) | ALDH1A1MAPTPOLBNPC1RAB9A | |
| SCHEMBL4893401 | 0.82 | CNR2 (0.39) | ALDH1A1MAPTPOLBNPC1RAB9A | |
| SCHEMBL4768461 | 0.79 | ALDH1A1 (0.38) | ALDH1A1MAPTPOLBNPC1RAB9A | |
| SCHEMBL4641222 | 0.79 | MTNR1A (0.45) | ALDH1A1MAPTPOLBNPC1RAB9A | |
| SCHEMBL4642278 | 0.78 | ALDH1A1 (0.39) | ALDH1A1MAPTPOLBNPC1RAB9A | |
| SCHEMBL4907971 | 0.77 | TBXAS1 (0.37) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269281-A1 | Novel Beta-Agonists, Method for Producing Them and Their Use as Drugs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269281-A1 | Novel Beta-Agonists, Method for Producing Them and Their Use as Drugs | ADRB3, ADRB2, ADRB1 | ALDH1A1 1087/4885MAPT 4073/4885POLB 2057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.