SCHEMBL489178

SCHEMBL489178

CCc1ccc(OBOc2ccc(CC)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.44
CYP2C19 P33261 1/20 0.44
TP53 P04637 1/20 0.42
ALDH1A1 P00352 2/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
CYP2A6 P11509 2/20 0.39
LPL P06858 1/20 0.39
LIPG Q9Y5X9 1/20 0.39
CYP1A2 P05177 1/20 0.38
RAB9A P51151 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
SOD1 P00441 1/20 0.38
NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18927002 0.81 SMN1; SMN2 (0.46) SMN1; SMN2CYP2C19TP53ALDH1A1LMNA
SCHEMBL3289628 0.81 THRB (0.47) ALDH1A1LMNATAAR1LPLLIPG
SCHEMBL769086 0.78 CA2 (0.47) SMN1; SMN2TP53ALDH1A1LMNAMAPT
SCHEMBL2334725 0.76 IDO1 (0.43) SMN1; SMN2TAAR1RAB9ANPC1
SCHEMBL1509992 0.76 ALDH1A1 (0.52) SMN1; SMN2TP53ALDH1A1LMNAMAPT
SCHEMBL16117387 0.76 SMN1; SMN2 (0.42) SMN1; SMN2CYP2C19ALDH1A1LMNAMAPT
SCHEMBL475215 0.76 SMN1; SMN2 (0.48) SMN1; SMN2CYP2C19TP53ALDH1A1LMNA
SCHEMBL8925998 0.76 SMN1; SMN2 (0.48) SMN1; SMN2CYP2C19TP53ALDH1A1LMNA
SCHEMBL11725689 0.76 TAAR1 (0.52) SMN1; SMN2CYP2C19TP53ALDH1A1LMNA
SCHEMBL27927558 0.75 TAAR1 (0.46) SMN1; SMN2CYP2C19TP53ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4263677-B1 METHODS AND SYSTEMS FOR PRODUCTION OF FURFURAL SHELL INT RESEARCH (NL) 2024-10-30 EP claimed
EP-4263676-B1 METHODS AND SYSTEMS FOR PRODUCTION OF FURFURAL SHELL INT RESEARCH (NL) 2024-10-30 EP claimed
US-20240025871-A1 METHODS AND SYSTEMS FOR PRODUCTION OF FURFURAL SHELL USA, INC. 2024-01-25 US claimed
EP-4263676-A1 METHODS AND SYSTEMS FOR PRODUCTION OF FURFURAL Shell Internationale Research Maatschappij B.V. (NL) 2023-10-25 EP claimed
EP-4263677-A1 METHODS AND SYSTEMS FOR PRODUCTION OF FURFURAL Shell Internationale Research Maatschappij B.V. (NL) 2023-10-25 EP claimed
WO-2022133271-A1 METHODS AND SYSTEMS FOR PRODUCTION OF FURFURAL SHELL OIL COMPANY (US) 2022-06-23 WO claimed
WO-2022133243-A1 METHODS AND SYSTEMS FOR PRODUCTION OF FURFURAL SHELL OIL COMPANY (US) 2022-06-23 WO claimed
US-20220194914-A1 METHODS AND SYSTEMS FOR PRODUCTION OF FURFURAL SHELL OIL COMPANY 2022-06-23 US claimed
CN-111362805-A Method for synthesizing biphenyl compounds by taking phenol as raw material 遵义医科大学 2020-07-03 CN claimed
CN-111253234-A Method for synthesizing biphenyl compounds by taking suaeda salsa extract liquid as solvent 遵义医科大学 2020-06-09 CN claimed
US-20250282735-A1 BICYCLE COMPOUNDS AS TEAD INHIBITOR DONG-A ST CO., LTD. (KR) 2025-09-11 US disclosed
US-20250092058-A1 MATTER OF COMPOSITION, SYNTHESIS, FORMULATION AND APPLICATION OF FL 118 PLATFORM POSITIONS 7 AND 9-DERIVED ANALOGUES FOR TREATMENT OF HUMAN DISEASE CANGET BIOTEKPHARMA, LLC 2025-03-20 US disclosed
CN-114555594-B Substituted azacycles as TRMP modulators 奇华顿股份有限公司 2025-03-18 CN disclosed
US-12187735-B2 Matter of composition, synthesis, formulation and application of FL118 platform positions 7 and 9-derived analogues for treatment of human disease CANGET BIOTEKPHARMA LLC (US) 2025-01-07 US disclosed
EP-4263676-B1 METHODS AND SYSTEMS FOR PRODUCTION OF FURFURAL SHELL INT RESEARCH (NL) 2024-10-30 EP disclosed
EP-0445257-A1 PYRIDINE DERIVATIVES AND A LIQUID CRYSTAL MEDIUM. MERCK PATENT GMBH (DE) 1991-09-11 EP disclosed
WO-1991004249-A1 PYRIDINE DERIVATIVES AND A LIQUID CRYSTAL MEDIUM MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-04-04 WO disclosed
EP-0199260-B1 BORONIC ACID ADDUCTS OF TECHNETIUM-99M DIOXIME COMPLEXES E.R. Squibb & Sons, Inc. (US) 1989-12-06 EP disclosed
US-4705849-A Boronic acid adducts of technetium-99m dioxime complexes E. R. SQUIBB & SONS, INC. (US) 1987-11-10 US disclosed
EP-0199260-A2 Boronic acid adducts of technetium-99M dioxime complexes E.R. Squibb & Sons, Inc. (US) 1986-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12187735-B2 Matter of composition, synthesis, formulation and application of FL118 platform positions 7 and 9-derived analogues for treatment of human disease TP53, BRCA1, MET SMN1; SMN2 499/4885CYP2C19 4533/4885TP53 1/4885
US-20250282735-A1 BICYCLE COMPOUNDS AS TEAD INHIBITOR TEAD1, TEAD2, TEAD3 SMN1; SMN2 3777/4885CYP2C19 33/4885TP53 948/4885
US-20250092058-A1 MATTER OF COMPOSITION, SYNTHESIS, FORMULATION AND APPLICATION OF FL 118 PLATFORM POSITIONS 7 AND 9-DERIVED ANALOGUES FOR TREATMENT OF HUMAN DISEASE FLNA, FLNB, FLI1 SMN1; SMN2 23/4885CYP2C19 4802/4885TP53 22/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.