SCHEMBL4896501

SCHEMBL4896501

O=S(=O)(ON=C(c1ccccc1)C(F)(F)S(=O)(=O)c1ccccc1)c1cccs1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
MAPT P10636 1/20 0.37
LMNA P02545 3/20 0.37
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
NPSR1 Q6W5P4 1/20 0.36
PKM P14618 1/20 0.35
KDM4E B2RXH2 1/20 0.35
TSHR P16473 1/20 0.34
POLB P06746 1/20 0.34
F2 P00734 2/20 0.34
PRSS1 P07477 2/20 0.34
PRSS2 P07478 2/20 0.34
PRSS3 P35030 2/20 0.34
NR1H2 P55055 1/20 0.33
MMP1 P03956 1/20 0.33
MMP9 P14780 1/20 0.33
MMP13 P45452 1/20 0.33
RORA P35398 1/20 0.33
RORC P51449 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4897641 0.79 KMT2A (0.36) ALDH1A1MAPTLMNAKMT2AMEN1
SCHEMBL4891641 0.78 KMT2A (0.35) ALDH1A1MAPTLMNAKMT2AMEN1
SCHEMBL4900892 0.78 KMT2A (0.42) ALDH1A1MAPTLMNAKMT2AMEN1
SCHEMBL4902695 0.76 PSIP1 (0.35) ALDH1A1MAPTKMT2AMEN1NPSR1
SCHEMBL4901088 0.75 F2 (0.37) MAPTKMT2AKDM4ETSHRF2
SCHEMBL6876264 0.74 RAB9A (0.36) ALDH1A1MAPTLMNAKMT2AMEN1
SCHEMBL4895537 0.72 TDP1 (0.35) ALDH1A1MAPTKMT2AMEN1NPSR1
SCHEMBL6880057 0.71 GAA (0.43) ALDH1A1MAPTKMT2AMEN1NPSR1
SCHEMBL6873824 0.71 PTGS2 (0.36) MAPTKMT2AMEN1POLBMMP1
SCHEMBL4903202 0.70 HSD11B1 (0.45) ALDH1A1MAPTKMT2APKMMMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6824954-B2 DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS JSR CORPORATION (JP) 2004-11-30 US claimed
US-20030113660-A1 Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same JSR CORPORATION (JP) 2003-06-19 US claimed
US-20080187859-A1 Radiation-Sensitive Resin Composition JSR CORPORATION (JP) 2008-08-07 US disclosed
US-20070269735-A1 Radiation-Sensitive Resin Composition JSR CORPORATION (JP) 2007-11-22 US disclosed
US-7297461-B2 Radiation sensitive resin composition JSR CORPORATION (JP) 2007-11-20 US disclosed
EP-1736829-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2006-12-27 EP disclosed
EP-1726608-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2006-11-29 EP disclosed
US-20050171226-A1 Radiation sensitive resin composition JSR CORPORATION (JP) 2005-08-04 US disclosed
US-6824954-B2 DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS JSR CORPORATION (JP) 2004-11-30 US disclosed
US-20030113660-A1 Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same JSR CORPORATION (JP) 2003-06-19 US disclosed