SCHEMBL4896749

SCHEMBL4896749

CC[N+](C)(C)C.CS(=O)(=O)O

nearest known ligand 0.42

Known targets — ChEMBL curated mechanism

ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC6A4 known ✓ P31645 1/20 0.42
CA2 P00918 3/20 0.37
BBOX1 O75936 2/20 0.32
TSHR P16473 1/20 0.32
KDM4E B2RXH2 1/20 0.31
CYP3A4 P08684 1/20 0.31
CA5A P35218 1/20 0.31
CA5B Q9Y2D0 1/20 0.31
CA1 P00915 3/20 0.31
CYP2C19 P33261 1/20 0.31
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
APEX1 P27695 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL9350051 0.90 CA5A (0.43) SLC6A4BBOX1TSHRKDM4ECA5A
Sulfuric Acid SCHEMBL3467201 0.84 TSHR (0.47) SLC6A4BBOX1TSHRALDH1A1
SCHEMBL4886484 0.84 BBOX1 (0.36) SLC6A4CA2BBOX1CA1
Sulfuric Acid SCHEMBL28984262 0.81 MEN1 (0.44) SLC6A4BBOX1TSHRALDH1A1
SCHEMBL1293415 0.80 BBOX1 (0.42) SLC6A4BBOX1KDM4ECYP3A4LMNA
Tetrylammonium SCHEMBL331444 0.80 TSHR (0.53) SLC6A4CA2TSHRKDM4ECYP3A4
SCHEMBL5403395 0.80 SLC6A4 (0.42) SLC6A4BBOX1KDM4ECYP3A4
SCHEMBL5403393 0.80 SLC6A4 (0.42) SLC6A4BBOX1KDM4ECYP3A4
Tetramethylammonium Ion SCHEMBL241976 0.78 CA2 (0.47) SLC6A4CA2TSHRKDM4ECYP3A4
Propane SCHEMBL27436764 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080033209-A1 Method For High-Purity Quaternary Ammonium Compounds BASF AKTIENGSELLSCHAFT (DE) 2008-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080033209-A1 Method For High-Purity Quaternary Ammonium Compounds ATL3, SMYD3, SP1 SLC6A4 1631/4885CA2 1027/4885BBOX1 3638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.