SCHEMBL4886484

SCHEMBL4886484

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nearest known ligand 0.36

Known targets — ChEMBL curated mechanism

ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC6A4 known ✓ P31645 1/20 0.35
BBOX1 O75936 2/20 0.36
CA2 P00918 3/20 0.35
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CA1 P00915 2/20 0.30
TERT O14746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL17102659 0.90 CA5A (0.40) BBOX1SLC6A4
Sulfuric Acid SCHEMBL7108309 0.85 MEN1 (0.44) BBOX1MEN1KMT2A
SCHEMBL4896749 0.84 SLC6A4 (0.42) BBOX1CA2SLC6A4CA1
SCHEMBL4657818 0.81 BBOX1 (0.41) BBOX1SLC6A4
SCHEMBL27512715 0.80 BBOX1 (0.32) BBOX1CA2CA1
Trifluoromethanesulfonic Acid SCHEMBL1861472 0.78 ALDH1A1 (0.33) BBOX1
Tetrylammonium SCHEMBL331444 0.78 TSHR (0.53) CA2SLC6A4CA1
Sulfuric Acid SCHEMBL7641807 0.78 BBOX1 (0.42) BBOX1SLC6A4
SCHEMBL28569345 0.76 CA1 (0.39) BBOX1CA2CA1
Tetramethylammonium Ion SCHEMBL241976 0.75 CA2 (0.47) CA2SLC6A4MEN1KMT2ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080033209-A1 Method For High-Purity Quaternary Ammonium Compounds BASF AKTIENGSELLSCHAFT (DE) 2008-02-07 US disclosed
US-20080009633-A1 Method for Producing High-Purity Quaternary Ammonium Compounds BASF AKTIENGESELLSCHAFT (DE) 2008-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080033209-A1 Method For High-Purity Quaternary Ammonium Compounds ATL3, SMYD3, SP1 SLC6A4 1631/4885BBOX1 3638/4885CA2 1027/4885
US-20080009633-A1 Method for Producing High-Purity Quaternary Ammonium Compounds SP1, EIF3A, EIF3H SLC6A4 2841/4885BBOX1 4160/4885CA2 346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.