Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9772954 | 0.85 | ALDH1A1 (0.51) | ALDH1A1LMNARAB9ANPC1TP53 | |
| SCHEMBL6576391 | 0.83 | ALDH1A1 (0.58) | ALDH1A1RAB9ATP53SMN1; SMN2HCAR3 | |
| SCHEMBL19728680 | 0.81 | HCAR3 (0.66) | ALDH1A1LMNARAB9ANPC1TP53 | |
| SCHEMBL3466195 | 0.80 | NNMT (0.63) | ALDH1A1LMNARAB9ANPC1TP53 | |
| SCHEMBL14020794 | 0.79 | HCAR3 (0.71) | ALDH1A1TP53HCAR3HCAR2HIF1A | |
| SCHEMBL19728674 | 0.79 | ALDH1A1 (0.56) | ALDH1A1LMNARAB9ANPC1TP53 | |
| SCHEMBL25543874 | 0.79 | ALDH1A1 (0.53) | ALDH1A1LMNARAB9ANPC1TP53 | |
| SCHEMBL19699552 | 0.76 | L3MBTL1 (0.68) | ALDH1A1LMNARAB9ANPC1TP53 | |
| SCHEMBL9891790 | 0.74 | RAB9A (0.68) | ALDH1A1LMNARAB9ANPC1TP53 | |
| SCHEMBL9769258 | 0.73 | RAB9A (0.55) | ALDH1A1LMNARAB9ANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255364-A1 | Method For The Production A-Chloroalkylpyridyl Ketones And/Or The Hydrochlorides Thereof | BASF AKTIENGESELLSCHAFT (DE) | 2008-10-16 | — | — | US | claimed |
| CN-1956957-A | Method for the production of a-chloroalkylpyridyl ketones and/or the hydrochlorides thereof | BASF AG (DE) | 2007-05-02 | — | — | CN | claimed |
| EP-1751110-A1 | METHOD FOR THE PRODUCTION OF A-CHLOROALKYLPYRIDYL KETONES AND/OR THE HYDROCHLORIDES THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2007-02-14 | — | — | EP | claimed |
| WO-2005113505-A1 | METHOD FOR THE PRODUCTION OF A-CHLOROALKYLPYRIDYL KETONES AND/OR THE HYDROCHLORIDES THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2005-12-01 | — | — | WO | claimed |
| US-20080255364-A1 | Method For The Production A-Chloroalkylpyridyl Ketones And/Or The Hydrochlorides Thereof | BASF AKTIENGESELLSCHAFT (DE) | 2008-10-16 | — | — | US | disclosed |
| CN-1956957-A | Method for the production of a-chloroalkylpyridyl ketones and/or the hydrochlorides thereof | BASF AG (DE) | 2007-05-02 | — | — | CN | disclosed |
| EP-1751110-A1 | METHOD FOR THE PRODUCTION OF A-CHLOROALKYLPYRIDYL KETONES AND/OR THE HYDROCHLORIDES THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005113505-A1 | METHOD FOR THE PRODUCTION OF A-CHLOROALKYLPYRIDYL KETONES AND/OR THE HYDROCHLORIDES THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2005-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255364-A1 | Method For The Production A-Chloroalkylpyridyl Ketones And/Or The Hydrochlorides Thereof | CBS, PCCA, ALK | ALDH1A1 620/4885LMNA 452/4885RAB9A 1394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.