SCHEMBL4899581

SCHEMBL4899581

Cc1ccc(S(=O)(=O)ON=C(c2ccccc2)C(F)(Cl)C#N)cc1

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.37
MEN1 O00255 3/20 0.37
LMNA P02545 4/20 0.36
KDM4E B2RXH2 4/20 0.36
RECQL P46063 2/20 0.36
MAPT P10636 3/20 0.36
ALDH1A1 P00352 10/20 0.35
MAPK1 P28482 1/20 0.34
POLB P06746 1/20 0.34
TDP1 Q9NUW8 2/20 0.34
TP53 P04637 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NOD2 Q9HC29 1/20 0.34
VDR P11473 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16063707 0.84 LMNA (0.42) KMT2AMEN1LMNAKDM4ERECQL
SCHEMBL4903378 0.81 KMT2A (0.38) KMT2AMEN1LMNAKDM4ERECQL
SCHEMBL4900892 0.81 KMT2A (0.42) KMT2AMEN1LMNAKDM4ERECQL
SCHEMBL547034 0.79 MAPT (0.44) KMT2AMEN1LMNAKDM4ERECQL
SCHEMBL547035 0.79 MAPT (0.44) KMT2AMEN1LMNAKDM4ERECQL
SCHEMBL1227015 0.79 LMNA (0.42) KMT2AMEN1LMNAKDM4ERECQL
SCHEMBL35981 0.79 LMNA (0.42) KMT2AMEN1LMNAKDM4ERECQL
SCHEMBL35980 0.79 LMNA (0.42) KMT2AMEN1LMNAKDM4ERECQL
SCHEMBL4902635 0.78 ALDH1A1 (0.37) KMT2AMEN1LMNAKDM4EALDH1A1
SCHEMBL4891573 0.78 ENPP3 (0.40) KMT2AMEN1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6824954-B2 DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS JSR CORPORATION (JP) 2004-11-30 US claimed
US-20030113660-A1 Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same JSR CORPORATION (JP) 2003-06-19 US claimed
US-20080187859-A1 Radiation-Sensitive Resin Composition JSR CORPORATION (JP) 2008-08-07 US disclosed
US-20070269735-A1 Radiation-Sensitive Resin Composition JSR CORPORATION (JP) 2007-11-22 US disclosed
US-7297461-B2 Radiation sensitive resin composition JSR CORPORATION (JP) 2007-11-20 US disclosed
EP-1736829-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2006-12-27 EP disclosed
EP-1726608-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2006-11-29 EP disclosed
US-20050171226-A1 Radiation sensitive resin composition JSR CORPORATION (JP) 2005-08-04 US disclosed
US-6824954-B2 DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS JSR CORPORATION (JP) 2004-11-30 US disclosed
US-20030113660-A1 Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same JSR CORPORATION (JP) 2003-06-19 US disclosed