Urethane

Urethane

SCHEMBL4903019

CCOC(N)=O.O=C(O)CCCCC(=O)ON1C(=O)CCC1=O.OCCO

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.38
PSMB8 P28062 1/20 0.33
PSMB5 P28074 1/20 0.33
KMT2A Q03164 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP1A2 P05177 1/20 0.33
TDP1 Q9NUW8 2/20 0.31
TSHR P16473 1/20 0.31
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
PAM P19021 2/20 0.31
ABL1 P00519 1/20 0.31
RIN1 Q13671 1/20 0.31
ALDH1A1 P00352 3/20 0.30
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
GPR84 Q9NQS5 1/20 0.30
FFAR1 O14842 1/20 0.30
FFAR4 Q5NUL3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urethane SCHEMBL4904899 0.97 ALOX15 (0.38) ALOX15PSMB8PSMB5KMT2ASMN1; SMN2
Urethane SCHEMBL4909069 0.92 ALOX15 (0.40) ALOX15PSMB8PSMB5KMT2AKDM4E
Urea SCHEMBL4916163 0.88 GPR84 (0.36) ALOX15PSMB8PSMB5KMT2ASMN1; SMN2
Urea SCHEMBL4905652 0.85 TSHR (0.37) PSMB8PSMB5KMT2ATSHRMEN1
Ethylene Glycol SCHEMBL28342229 0.85 GPR84 (0.42) PSMB8PSMB5KMT2ASMN1; SMN2TSHR
Ethylene Glycol SCHEMBL28881509 0.85 GPR84 (0.42) PSMB8PSMB5KMT2ASMN1; SMN2TSHR
Ethylene Glycol SCHEMBL6129445 0.84 TSHR (0.40) PSMB8PSMB5KMT2ASMN1; SMN2CYP1A2
SCHEMBL290460 0.82 LMNA (0.41) KMT2ASMN1; SMN2TSHRMEN1GAA
SCHEMBL25406852 0.81 TSHR (0.43) ALOX15KMT2ASMN1; SMN2TDP1TSHR
SCHEMBL25407766 0.81 TSHR (0.43) ALOX15KMT2ASMN1; SMN2TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080159975-A1 Hair treatment composition, hair treatment agent and method for treating hair by using the same SUNBIO, INC. (KR) 2008-07-03 US claimed
EP-1938795-A2 Hair treatment composition, hair treatment agent and method for treating hair by using the same Sunbio, Inc. (KR) 2008-07-02 EP claimed
US-20080159975-A1 Hair treatment composition, hair treatment agent and method for treating hair by using the same SUNBIO, INC. (KR) 2008-07-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080159975-A1 Hair treatment composition, hair treatment agent and method for treating hair by using the same KRT18, CUTA, KRTCAP2 ALOX15 1429/4885PSMB8 1560/4885PSMB5 1049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.