Urethane

Urethane

SCHEMBL4904899

CCOC(N)=O.O=C(O)CCCC(=O)ON1C(=O)CCC1=O.OCCO

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.34
PSMB8 P28062 1/20 0.33
PSMB5 P28074 1/20 0.33
KDM4E B2RXH2 2/20 0.33
CYP1A2 P05177 1/20 0.33
SMYD3 Q9H7B4 1/20 0.32
KMT2A Q03164 3/20 0.31
RAB9A P51151 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ALDH1A1 P00352 3/20 0.30
MEN1 O00255 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
GAA P10253 1/20 0.30
POLB P06746 1/20 0.30
KYAT1 Q16773 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urethane SCHEMBL4903019 0.97 ALOX15 (0.38) ALOX15TSHRPSMB8PSMB5KDM4E
Urethane SCHEMBL4909069 0.92 ALOX15 (0.40) ALOX15TSHRPSMB8PSMB5KDM4E
Urea SCHEMBL4905652 0.88 TSHR (0.37) TSHRPSMB8PSMB5KMT2AMEN1
Ethylene Glycol SCHEMBL6129445 0.87 TSHR (0.40) TSHRPSMB8PSMB5CYP1A2KMT2A
Urea SCHEMBL4916163 0.85 GPR84 (0.36) ALOX15TSHRPSMB8PSMB5KMT2A
Ethylene Glycol SCHEMBL28881509 0.82 GPR84 (0.42) TSHRPSMB8PSMB5KMT2AALDH1A1
Ethylene Glycol SCHEMBL28342229 0.82 GPR84 (0.42) TSHRPSMB8PSMB5KMT2AALDH1A1
SCHEMBL34382 0.82 TSHR (0.44) TSHRPSMB8PSMB5CYP1A2KMT2A
SCHEMBL6358200 0.81 CYP1A2 (0.46) TSHRKDM4ECYP1A2SMYD3KMT2A
Ethylene Glycol SCHEMBL6523939 0.81 PSMB8 (0.34) TSHRPSMB8PSMB5KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080159975-A1 Hair treatment composition, hair treatment agent and method for treating hair by using the same SUNBIO, INC. (KR) 2008-07-03 US claimed
EP-1938795-A2 Hair treatment composition, hair treatment agent and method for treating hair by using the same Sunbio, Inc. (KR) 2008-07-02 EP claimed
US-20080159975-A1 Hair treatment composition, hair treatment agent and method for treating hair by using the same SUNBIO, INC. (KR) 2008-07-03 US disclosed
EP-1938795-A2 Hair treatment composition, hair treatment agent and method for treating hair by using the same Sunbio, Inc. (KR) 2008-07-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080159975-A1 Hair treatment composition, hair treatment agent and method for treating hair by using the same KRT18, CUTA, KRTCAP2 ALOX15 1429/4885TSHR 3358/4885PSMB8 1560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.