SCHEMBL4903129

SCHEMBL4903129

Cc1ccc(S(=O)(=O)ON=C(c2ccccc2)C(F)(Cl)[S+]([O-])C2CCCCC2)cc1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 5/20 0.34
KMT2A Q03164 5/20 0.34
APLNR P35414 2/20 0.34
ENPP3 O14638 2/20 0.33
ENPP1 P22413 2/20 0.33
ENPP2 Q13822 2/20 0.33
RAB9A P51151 1/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2C19 P33261 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
POLB P06746 1/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4902635 0.84 ALDH1A1 (0.37) ALDH1A1MEN1KMT2AAPLNRENPP3
SCHEMBL4891573 0.81 ENPP3 (0.40) ALDH1A1MEN1KMT2AAPLNRENPP3
SCHEMBL4901721 0.80 ALDH1A1 (0.37) ALDH1A1MEN1KMT2AAPLNRENPP3
SCHEMBL16063707 0.77 LMNA (0.42) ALDH1A1MEN1KMT2ARAB9ATDP1
SCHEMBL4899581 0.75 KMT2A (0.37) ALDH1A1MEN1KMT2ATDP1POLB
SCHEMBL4903378 0.75 KMT2A (0.38) ALDH1A1MEN1KMT2ATDP1POLB
SCHEMBL4900892 0.74 KMT2A (0.42) ALDH1A1MEN1KMT2ARAB9ATDP1
SCHEMBL547035 0.72 MAPT (0.44) ALDH1A1MEN1KMT2ARAB9ACYP3A4
SCHEMBL547034 0.72 MAPT (0.44) ALDH1A1MEN1KMT2ARAB9ACYP3A4
SCHEMBL13037415 0.68 STAT3 (0.47) ALDH1A1MEN1KMT2ARAB9ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6824954-B2 DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS JSR CORPORATION (JP) 2004-11-30 US claimed
US-20030113660-A1 Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same JSR CORPORATION (JP) 2003-06-19 US claimed
US-20080187859-A1 Radiation-Sensitive Resin Composition JSR CORPORATION (JP) 2008-08-07 US disclosed
US-20070269735-A1 Radiation-Sensitive Resin Composition JSR CORPORATION (JP) 2007-11-22 US disclosed
US-7297461-B2 Radiation sensitive resin composition JSR CORPORATION (JP) 2007-11-20 US disclosed
EP-1736829-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2006-12-27 EP disclosed
EP-1726608-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2006-11-29 EP disclosed
US-20050171226-A1 Radiation sensitive resin composition JSR CORPORATION (JP) 2005-08-04 US disclosed
US-6824954-B2 DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS JSR CORPORATION (JP) 2004-11-30 US disclosed
US-20030113660-A1 Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same JSR CORPORATION (JP) 2003-06-19 US disclosed