SCHEMBL4903379

SCHEMBL4903379

C=CCNC(=S)NC(=O)c1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.75
ALDH1A1 P00352 5/20 0.62
SMN1; SMN2 Q16637 5/20 0.62
ALOX12 P18054 3/20 0.62
LMNA P02545 2/20 0.62
HPGD P15428 1/20 0.62
MITF O75030 1/20 0.62
RAB9A P51151 2/20 0.59
NPSR1 Q6W5P4 1/20 0.59
EPHX1 P07099 1/20 0.58
NPC1 O15118 1/20 0.55
CA1 P00915 2/20 0.55
CA9 Q16790 2/20 0.55
GAA P10253 1/20 0.55
KDM4E B2RXH2 1/20 0.55
MAPT P10636 1/20 0.55
MEN1 O00255 1/20 0.55
RECQL P46063 1/20 0.55
KMT2A Q03164 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4970119 0.83 LMNA (0.66) POLBALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL10526111 0.83 POLB (0.60) POLBALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL83922 0.83 HPGD (0.86) POLBALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL9771178 0.83 ALDH1A1 (0.60) POLBALDH1A1SMN1; SMN2ALOX12LMNA
SCHEMBL11323872 0.82 SMN1; SMN2 (0.64) POLBALDH1A1SMN1; SMN2ALOX12LMNA
SCHEMBL15328470 0.81 ALDH1A1 (0.78) ALDH1A1SMN1; SMN2ALOX12LMNAMITF
SCHEMBL1074279 0.81 LMNA (0.62) POLBALDH1A1SMN1; SMN2ALOX12LMNA
SCHEMBL38662723 0.80 ALDH1A1 (0.62) POLBALDH1A1SMN1; SMN2ALOX12LMNA
Ethylene SCHEMBL28911980 0.79 EPHX1 (0.69) ALDH1A1SMN1; SMN2ALOX12MITFRAB9A
SCHEMBL2348030 0.78 ALDH1A1 (0.68) POLBALDH1A1SMN1; SMN2ALOX12LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814366-B2 Antiviral compounds and use thereof UNIVERSITA DEGLI STUDI DI SIENA (IT) 2023-11-14 US disclosed
EP-3765454-B1 ANTIVIRAL COMPOUNDS AND USE THEREOF UNIV DEGLI STUDI DI SIENA (IT) 2023-11-08 EP disclosed
CN-110035829-B Depressant composition and method for depressing gangue sulfide minerals during flotation of sulfide ores 塞特工业公司 2021-12-24 CN disclosed
US-20210070737-A1 ANTIVIRAL COMPOUNDS AND USE THEREOF UNIVERSITA DEGLE STUDI DI SIENA (IT) 2021-03-11 US disclosed
US-10710099-B2 Compositions and methods for selective separation of minerals from sulfide ores CYTEC INDUSTRIES INC. (US) 2020-07-14 US disclosed
US-20190336984-A1 COMPOSITIONS AND METHODS FOR SELECTIVE SEPARATION OF MINERALS FROM SULFIDE ORES CYTEC INDUSTRIES INC. (US) 2019-11-07 US disclosed
US-10369577-B2 Compositions and methods for selective separation of minerals from sulfide ores CYTEC INDUSTRIES INC. (US) 2019-08-06 US disclosed
US-20180099293-A1 COMPOSITIONS AND METHODS FOR SELECTIVE SEPARATION OF MINERALS FROM SULFIDE ORES CYTEC INDUSTRIES INC. 2018-04-12 US disclosed
US-20080312435-A1 Imine Compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2008-12-18 US disclosed
US-20080312435-A1 Imine Compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2008-12-18 US disclosed
WO-1997035897-A1 NOVEL POLYMERIC SULFIDE MINERAL DEPRESSANTS CYTEC TECHNOLOGY CORP. (US) 1997-10-02 WO disclosed
EP-0338276-B1 Copolymers of acrylamide with allylthioureas as sulfide mineral depressants AMERICAN CYANAMID CO (US) 1994-05-18 EP disclosed
US-5019246-A Benefication by froth flotation; separation AMERICAN CYANAMID COMPANY (US) 1991-05-28 US disclosed
US-4966938-A FROTH FLOTATION DEPRESSANTS AMERICAN CYANAMID COMPANY (US) 1990-10-30 US disclosed
US-4902765-A Allyl thiourea polymers AMERICAN CYANAMID COMPANY (US) 1990-02-20 US disclosed
US-4888106-A FROTH FLOTATION AMERICAN CYANAMID COMPANY (US) 1989-12-19 US disclosed
EP-0338276-A2 Copolymers of acrylamide with allylthioureas as sulfide mineral depressants AMERICAN CYANAMID COMPANY (US) 1989-10-25 EP disclosed
US-4866150-A (METH)ACRYLAMIDE-THIOUREA POLYMERS AMERICAN CYANAMID COMPANY (US) 1989-09-12 US disclosed
US-4260552-A INSECTICIDES, HERBICIDES UNIROYAL, INC. (US) 1981-04-07 US disclosed
US-4160846-A Method for controlling insects with tetrasubstituted organotin compounds UNIROYAL, INC. (US) 1979-07-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080312435-A1 Imine Compound CNR1, CNR2, HRH4 POLB 4390/4885ALDH1A1 2674/4885SMN1; SMN2 1844/4885
US-11814366-B2 Antiviral compounds and use thereof MAVS, EIF2AK2, SARS1 POLB 136/4885ALDH1A1 2154/4885SMN1; SMN2 2276/4885
US-10369577-B2 Compositions and methods for selective separation of minerals from sulfide ores TST, CTH, PFAS POLB 4309/4885ALDH1A1 1471/4885SMN1; SMN2 1936/4885
US-20210070737-A1 ANTIVIRAL COMPOUNDS AND USE THEREOF MAVS, EIF2AK2, SARS1 POLB 136/4885ALDH1A1 2154/4885SMN1; SMN2 2276/4885
US-20190336984-A1 COMPOSITIONS AND METHODS FOR SELECTIVE SEPARATION OF MINERALS FROM SULFIDE ORES TST, CTH, PFAS POLB 4309/4885ALDH1A1 1471/4885SMN1; SMN2 1936/4885
US-10710099-B2 Compositions and methods for selective separation of minerals from sulfide ores TST, CTH, PFAS POLB 4309/4885ALDH1A1 1471/4885SMN1; SMN2 1936/4885
US-20180099293-A1 COMPOSITIONS AND METHODS FOR SELECTIVE SEPARATION OF MINERALS FROM SULFIDE ORES TST, CTH, PFAS POLB 4309/4885ALDH1A1 1471/4885SMN1; SMN2 1936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.