SCHEMBL490669

SCHEMBL490669

CCCC(CCCCCCCCCCCCCCOCCO)OC(CCC)CCCCCCCCCCCCCCOCCO

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
HTT P42858 2/20 0.57
THRB P10828 1/20 0.57
MAPT P10636 1/20 0.57
TSHR P16473 2/20 0.52
USP2 O75604 2/20 0.38
MAPK1 P28482 2/20 0.37
ALDH1A1 P00352 2/20 0.37
LMNA P02545 2/20 0.33
CYP3A4 P08684 1/20 0.33
CASP1 P29466 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SLCO1B3 Q9NPD5 1/20 0.33
SLCO1B1 Q9Y6L6 1/20 0.33
CES1 P23141 1/20 0.33
TLR2 O60603 1/20 0.33
LPAR6 P43657 3/20 0.33
LPAR1 Q92633 3/20 0.33
LPAR4 Q99677 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL491059 0.93 MEN1 (0.62) MEN1KMT2AHTTTHRBMAPT
SCHEMBL8772504 0.93 HTT (0.68) MEN1KMT2AHTTTHRBMAPT
SCHEMBL490565 0.93 HTT (0.68) MEN1KMT2AHTTTHRBMAPT
Triethylene Glycol SCHEMBL25307288 0.91 MEN1 (0.60) MEN1KMT2AHTTTHRBMAPT
Triethylene Glycol SCHEMBL25303227 0.91 MEN1 (0.60) MEN1KMT2AHTTTHRBMAPT
Triethylene Glycol SCHEMBL25260216 0.89 MEN1 (0.57) MEN1KMT2AHTTTHRBMAPT
Di(Hydroxyethyl)Ether SCHEMBL4421030 0.89 TSHR (0.56) MEN1KMT2AHTTTHRBMAPT
Di(Hydroxyethyl)Ether SCHEMBL5146482 0.89 MEN1 (0.61) MEN1KMT2AHTTTHRBMAPT
Di(Hydroxyethyl)Ether SCHEMBL4425237 0.88 TSHR (0.52) MEN1KMT2AHTTTHRBMAPT
SCHEMBL491019 0.87 MEN1 (0.53) MEN1KMT2AHTTTHRBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020216641-A1 A HAIR WAX COMPOSITION BEIERSDORF AG (DE) 2020-10-29 WO claimed
CN-113164797-B Novel cosmetic and dermatological use of Cistus polyrhachis extract 巴斯夫美容护理法国公司 2024-05-28 CN disclosed
CN-114555042-B Novel cosmetic use of N-methylglycine for increasing the diversity of the microbial flora of the skin 巴斯夫美容护理法国公司 2024-03-05 CN disclosed
CN-109715192-B Drug conjugates for converting neoplastic cells to non-neoplastic cells and uses thereof 伊斯迪德股份公司 2024-02-20 CN disclosed
CN-117482133-A New cosmetic or dermatological use of extract of Gentiana macrophylla Franch 巴斯夫美容护理法国公司 2024-02-02 CN disclosed
CN-117379347-A Cosmetic or dermatological use of pyracantha fortuneana extract 巴斯夫美容护理法国公司 2024-01-12 CN disclosed
CN-116831962-A Cosmetic or dermatological use of Dendrobium officinale extract for maintaining and/or increasing skin thickness 巴斯夫美容护理法国公司 2023-10-03 CN disclosed
CN-116685307-A Cosmetic, nutritional or dermatological use of lactobacillus crispatus strains and/or compositions comprising the same 巴斯夫美容护理法国公司 2023-09-01 CN disclosed
CN-112236201-B Use of extract of rosewood (BIXA ORELLANA) 巴斯夫美容护理法国公司 2023-08-29 CN disclosed
CN-108883055-B Cosmetic use of African chinaberry extract 巴斯夫美容护理法国公司 2023-06-02 CN disclosed
US-20040037797-A1 Water-in-oil emulsions containing one or more ammonium acryloylodimethyltaurate/vinylpyrrolidone copolymers BEIERSDORF AG 2004-02-26 US disclosed
US-6620420-B2 Cosmetic or dermatological application BEIERSDORF AG (DE) 2003-09-16 US disclosed
US-20030147928-A1 Water, oil in water emulsifiers, optionally coemulsifiers, oil phase(s), polidocanol and an essential oil; saturated cloth; immediate and long-lasting effect BEIERSDORF AG 2003-08-07 US disclosed
US-20030091605-A1 Use of alpha-lipoic acid for producing cosmetic or dermatological preparations for regenerating stressed skin, in particular aged skin BEIERSDORF AG 2003-05-15 US disclosed
US-20030012801-A1 Active ingredient combinations of surface-active citric esters and inclusion compounds of cyclodextrins and retinoids, and cosmetic and dermatological preparations containing such mixtures BEIERSDORF AG 2003-01-16 US disclosed
US-20020176832-A1 O/W emulsions containing one or more ammonium acryloyldimethyltaurate/vinylpyrrolidone copolymers CLARIANT INTERNATIONAL LTD. (CH) 2002-11-28 US disclosed
US-20020155076-A1 Gel creams in the form of O/W emulsions containing one or more ammonium acryloyldimethyltaurate/vinylpyrrolidone copolymers CLARIANT INTERNATIONAL LTD. (CH) 2002-10-24 US disclosed
US-20020119114-A1 Active ingredient combinations of surface-active citric esters and alpha-lipoic acid, and cosmetic and dermatological preparations containing such mixtures BEIERSDORF AKTIENGESELLSCHAFT 2002-08-29 US disclosed
US-6436414-B1 Active ingredient combinations or adducts of biotin and/or biotin derivatives and cyclodextrins and use of such active ingredient combinations in cosmetic preparations BEIERSDORF AG (DE) 2002-08-20 US disclosed
US-20020045596-A1 Active ingredient combinations or adducts of cyclodextrins and at least one quinone and/or at least one hydroquinone and use of such active ingredient combinations in cosmetic preparations BEIERSDORF AG (DE) 2002-04-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020045596-A1 Active ingredient combinations or adducts of cyclodextrins and at least one quinone and/or at least one hydroquinone and use of such active ingredient combinations in cosmetic preparations NQO1, RECQL, KEAP1 MEN1 2565/4885KMT2A 3530/4885HTT 235/4885
US-20030012801-A1 Active ingredient combinations of surface-active citric esters and inclusion compounds of cyclodextrins and retinoids, and cosmetic and dermatological preparations containing such mixtures ALDH1A2, GAA, GCDH MEN1 3273/4885KMT2A 4662/4885HTT 3635/4885
US-20020176832-A1 O/W emulsions containing one or more ammonium acryloyldimethyltaurate/vinylpyrrolidone copolymers AGPAT2, PHOSPHO1, MBOAT1 MEN1 4169/4885KMT2A 743/4885HTT 595/4885
US-20020155076-A1 Gel creams in the form of O/W emulsions containing one or more ammonium acryloyldimethyltaurate/vinylpyrrolidone copolymers AGPAT2, ACMSD, POLR1C MEN1 4477/4885KMT2A 1076/4885HTT 304/4885
US-20020119114-A1 Active ingredient combinations of surface-active citric esters and alpha-lipoic acid, and cosmetic and dermatological preparations containing such mixtures LIPA, GLA, DEGS1 MEN1 1433/4885KMT2A 2016/4885HTT 2257/4885
US-20030091605-A1 Use of alpha-lipoic acid for producing cosmetic or dermatological preparations for regenerating stressed skin, in particular aged skin CUTA, LIPA, LPO MEN1 4447/4885KMT2A 4069/4885HTT 747/4885
US-20030147928-A1 Water, oil in water emulsifiers, optionally coemulsifiers, oil phase(s), polidocanol and an essential oil; saturated cloth; immediate and long-lasting effect POLD1, POLD3, POLI MEN1 4540/4885KMT2A 1719/4885HTT 3193/4885
US-20040037797-A1 Water-in-oil emulsions containing one or more ammonium acryloylodimethyltaurate/vinylpyrrolidone copolymers PHOSPHO1, AGPAT2, AGPAT5 MEN1 3181/4885KMT2A 1398/4885HTT 247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.