Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668032 | 0.82 | MEN1 (0.33) | ALDH1A1 | |
| SCHEMBL8817061 | 0.78 | HTR2A (0.34) | ALDH1A1 | |
| SCHEMBL1985195 | 0.69 | MEN1 (0.31) | — | |
| SCHEMBL6052739 | 0.67 | KEAP1 (0.35) | — | |
| SCHEMBL10785290 | 0.63 | MAOA (0.38) | ALDH1A1MAPT | |
| SCHEMBL4392662 | 0.63 | KDM4E (0.58) | ALDH1A1MAPT | |
| SCHEMBL7024322 | 0.61 | DRD2 (0.33) | ALDH1A1 | |
| SCHEMBL10924424 | 0.61 | ALDH1A1 (0.36) | ALDH1A1MAPT | |
| SCHEMBL24881042 | 0.59 | CRBN (0.51) | — | |
| SCHEMBL3809858 | 0.58 | KDM4E (0.55) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221158-A1 | Novel 14 and 15 Membered Ring Compounds | PLIVA - Istrazivacki Institut d.o.o | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221158-A1 | Novel 14 and 15 Membered Ring Compounds | IL17A, CYP51A1, IL15 | ALDH1A1 1819/4885MAPT 3621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.