Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PRKCA | P17252 | 6/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491474 | 0.86 | PRKCA (0.54) | PRKCAPRKCEPRKCQPRKCD | |
| SCHEMBL2568907 | 0.85 | MAPT (0.50) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL12199528 | 0.81 | MAPT (0.48) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL7321395 | 0.81 | MGAM (0.50) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL18026483 | 0.79 | MGAM (0.48) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL402501 | 0.79 | MAPT (0.57) | MAPTMAPK1PRKCAFAAHALDH1A1 | |
| SCHEMBL11328900 | 0.78 | MGAM (0.35) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL22124620 | 0.78 | MAPT (0.45) | MAPTMAPK1PRKCAFAAHALDH1A1 | |
| SCHEMBL648594 | 0.77 | ALDH1A1 (0.47) | MGAMGAASIMGAM2PRKCA | |
| SCHEMBL11125832 | 0.77 | PRKCA (0.38) | MAPTMAPK1PRKCAPRKCEPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11890264-B2 | Migraine prevention and treatment | UNIVERSITATS-KINDERSPITAL BEIDER BASEL (CH) | 2024-02-06 | — | — | US | claimed |
| US-20210338618-A1 | MIGRAINE PREVENTION AND TREATMENT | UNIVERSITATS-KINDERSPITAL BEIDER BASEL (CH) | 2021-11-04 | — | — | US | claimed |
| US-20250275986-A1 | COMBINATION OF A KETONE BODY OR KETOGENIC COMPOUND WITH AN ANALGESIC OR ANTIOXIDANT | KETOSWISS AG (CH) | 2025-09-04 | — | — | US | disclosed |
| US-12286534-B2 | Binder for an aqueous coating composition | ALLNEX AUSTRIA GMBH (AT) | 2025-04-29 | — | — | US | disclosed |
| US-20240425643-A1 | FOAM COMPOSITIONS | AMRIZE TECHNOLOGY SWITZERLAND LLC (CH) | 2024-12-26 | — | — | US | disclosed |
| US-12098240-B2 | Foam compositions | HOLCIM TECHNOLOGY LTD (CH) | 2024-09-24 | — | — | US | disclosed |
| US-12071498-B2 | Radically polymerizable compositions | Polynt Composites USA, Inc. (US) | 2024-08-27 | — | — | US | disclosed |
| EP-4373483-A1 | COMBINATION OF A KETONE BODY OR KETOGENIC COMPOUND WITH AN ANALGESIC OR ANTIOXIDANT | KetoSwiss AG (CH) | 2024-05-29 | — | — | EP | disclosed |
| CN-117677383-A | Combinations of ketone bodies or ketone-forming compounds, analgesics or antioxidants | 瑞士凯托股份公司 | 2024-03-08 | — | — | CN | disclosed |
| US-11890264-B2 | Migraine prevention and treatment | UNIVERSITATS-KINDERSPITAL BEIDER BASEL (CH) | 2024-02-06 | — | — | US | disclosed |
| CN-113474383-B | Free radical polymerizable composition | 波林复合材料美国股份有限公司 | 2023-10-31 | — | — | CN | disclosed |
| WO-2004091665-A1 | COMBINATION THERAPY FOR CONSTIPATION COMPRISING A LAXATIVE AND A PERIPHERAL OPIOID ANTAGONIST | PROGENICS PHARMACEUTICALS, INC. (US) | 2004-10-28 | — | — | WO | disclosed |
| US-4970143-A | BICARBONATE BUFFER SOLUTION | NESTEC S.A. (CH) | 1990-11-13 | — | — | US | disclosed |
| EP-0184905-B1 | 2-ACETOACETYLGLYCEROL DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1989-03-01 | — | — | EP | disclosed |
| US-4710579-A | ANTITUMOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-12-01 | — | — | US | disclosed |
| EP-0184905-A1 | 2-Acetoacetylglycerol derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-06-18 | — | — | EP | disclosed |
| EP-0184905-A1 | 2-Acetoacetylglycerol derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-06-18 | — | — | EP | disclosed |
| EP-0037943-B1 | PHARMACEUTICAL COMPOSITION FOR INTRARECTAL ADMINISTRATION, AND SUPPOSITORY PREPARED THEREFROM | TEIJIN LIMITED (JP) | 1985-08-14 | — | — | EP | disclosed |
| US-4434159-A | PEPTIDE HORMONES, POLYSACCHARIDES, ABSORPTION AIDS | TEIJIN LIMITED (JP) | 1984-02-28 | — | — | US | disclosed |
| EP-0037943-A2 | Pharmaceutical composition for intrarectal administration, and suppository prepared therefrom | TEIJIN LIMITED (JP) | 1981-10-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210338618-A1 | MIGRAINE PREVENTION AND TREATMENT | ACACA, ACACB, HBB | MGAM 2155/4885GAA 751/4885SI 906/4885 |
| US-11890264-B2 | Migraine prevention and treatment | ACACA, ACACB, HBB | MGAM 2155/4885GAA 751/4885SI 906/4885 |
| US-20250275986-A1 | COMBINATION OF A KETONE BODY OR KETOGENIC COMPOUND WITH AN ANALGESIC OR ANTIOXIDANT | PKM, KCNMA1, KCNK18 | MGAM 497/4885GAA 2246/4885SI 1007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.