Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 4/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL493647 | 0.93 | KDM4E (0.48) | LMNAPKMKMT2ASMN1; SMN2MAPT | |
| SCHEMBL494420 | 0.89 | LMNA (0.46) | LMNAPKMKMT2ASMN1; SMN2MAPT | |
| SCHEMBL493591 | 0.86 | SMN1; SMN2 (0.47) | LMNAPKMKMT2ASMN1; SMN2MAPT | |
| SCHEMBL493737 | 0.86 | KMT2A (0.49) | KMT2AMAPT | |
| SCHEMBL492913 | 0.86 | RAB9A (0.39) | KMT2ASMN1; SMN2MAPTCCR2 | |
| SCHEMBL493779 | 0.84 | SMN1; SMN2 (0.52) | LMNAPKMKMT2ASMN1; SMN2MAPT | |
| SCHEMBL494415 | 0.84 | TSHR (0.42) | PKMKMT2ASMN1; SMN2 | |
| SCHEMBL493600 | 0.84 | GHSR (0.40) | PKMKMT2AMAPTCCR2 | |
| SCHEMBL493820 | 0.83 | RAB9A (0.40) | SMN1; SMN2CCR2 | |
| SCHEMBL493461 | 0.82 | KDM4E (0.45) | LMNAPKMKMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106055-B2 | Substituted amide compounds | GRUENENTHAL GMBH (DE) | 2012-01-31 | — | — | US | claimed |