Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 8/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CCR2 | P41597 | 2/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | NR2E1 | Q9Y466 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717881 | 0.94 | TRPA1 (0.44) | TRPA1CYP1A2LMNAALDH1A1CCR2 | |
| SCHEMBL4923724 | 0.93 | LMNA (0.43) | TRPA1CYP1A2LMNAALDH1A1CCR2 | |
| SCHEMBL5104500 | 0.90 | ALDH1A1 (0.52) | LMNAALDH1A1THRATHRBACP1 | |
| SCHEMBL4929708 | 0.89 | TRPA1 (0.47) | TRPA1CYP1A2LMNAALDH1A1CCR2 | |
| SCHEMBL4931483 | 0.89 | TRPA1 (0.47) | TRPA1CYP1A2LMNAALDH1A1CCR2 | |
| SCHEMBL5109577 | 0.88 | LMNA (0.45) | LMNAALDH1A1THRATHRBACP1 | |
| SCHEMBL4931227 | 0.88 | LMNA (0.45) | LMNAALDH1A1CCR2THRATHRB | |
| SCHEMBL5717827 | 0.87 | THRA (0.45) | TRPA1CYP1A2LMNAALDH1A1CCR2 | |
| SCHEMBL4933736 | 0.87 | ALDH1A1 (0.44) | TRPA1CYP1A2ALDH1A1CCR2THRA | |
| SCHEMBL4929575 | 0.86 | LMNA (0.40) | TRPA1CYP1A2LMNAALDH1A1THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | TRPA1 675/4885CYP1A2 1307/4885LMNA 3893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.