Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.33 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.33 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4932767 | 0.91 | ALDH1A1 (0.46) | ALDH1A1THRBTHRACYP1A2CYP3A4 | |
| SCHEMBL4933128 | 0.89 | TRPA1 (0.41) | ALDH1A1TRPA1THRBTHRACYP1A2 | |
| SCHEMBL4931585 | 0.89 | THRB (0.43) | ALDH1A1TRPA1THRBTHRACYP1A2 | |
| SCHEMBL4930968 | 0.89 | ALDH1A1 (0.42) | ALDH1A1TRPA1THRBTHRAKMT2A | |
| SCHEMBL5111499 | 0.88 | ALDH1A1 (0.58) | ALDH1A1THRBTHRACYP1A2CYP3A4 | |
| SCHEMBL4929668 | 0.87 | TRPA1 (0.48) | ALDH1A1TRPA1THRBTHRACYP1A2 | |
| SCHEMBL5717833 | 0.86 | THRA (0.35) | ALDH1A1TRPA1THRBTHRACYP1A2 | |
| SCHEMBL5111642 | 0.86 | KMT2A (0.46) | ALDH1A1THRBTHRACYP1A2CYP3A4 | |
| SCHEMBL4931960 | 0.86 | ALDH1A1 (0.45) | ALDH1A1THRBTHRACYP1A2CYP3A4 | |
| SCHEMBL4926964 | 0.84 | ALDH1A1 (0.39) | ALDH1A1THRBTHRACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | ALDH1A1 1818/4885TRPA1 675/4885THRB 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.